Free Trivia FPGEE Exam Question and Answers

Question 1

What do IND and NDA, respectively, stand for?

Accepted Answer

Investigation New Drug, New Drug Application

Answer

In the pharmaceutical regulatory process, IND stands for Investigational New Drug. This application is submitted to the FDA before a drug can be tested in human clinical trials. NDA stands for New Drug Application, which is submitted to the FDA after successful clinical trials to request approval for marketing a new drug for public use.

Question 2

Venlafaxine is sold under the trade name Effexor. Vardenafil is sold under the brand name Levitra. The other matches are accurate.

Accepted Answer

Levitra-Venlafaxine

Answer

Levitra is the brand name for the drug Vardenafil, which is used to treat erectile dysfunction. Venlafaxine, on the other hand, is an antidepressant sold under the brand name Effexor. Therefore, the pairing of Levitra with Venlafaxine is incorrect, while the other brand-generic matches provided are accurate.

Question 3

Alcohol and metronidazole are reported to respond similarly to disulfiram. Which dosage type for metronidazole would be the best?

Accepted Answer

As a suspension

Answer

Metronidazole can cause a disulfiram-like reaction when consumed with alcohol, leading to unpleasant symptoms like flushing, nausea, and vomiting. To avoid any potential alcohol content, metronidazole should be administered in a dosage form that is entirely alcohol-free. A suspension is a suitable option, unlike spirits, fluid extracts, or tinctures, which typically contain alcohol.

Question 4

What is the gentamicin's mode of action?

Accepted Answer

It is an aminoglycoside and is bacteriocidal against Gram (-) bacteria by irreversibly binding the 30S subunit of bacterial ribosomes.

Answer

Gentamicin is an aminoglycoside antibiotic that exerts its bactericidal effects primarily against Gram-negative bacteria. Its mode of action involves irreversibly binding to the 30S ribosomal subunit of bacterial ribosomes. This binding disrupts bacterial protein synthesis, leading to the production of faulty proteins and ultimately bacterial cell death.

Question 5

Which of the following is not a lupus-like syndrome sign, symptom, or complication?

Accepted Answer

Arrhythmia

Answer

Lupus-like syndrome, particularly drug-induced lupus erythematosus, commonly presents with symptoms such as a red, scaly, macular rash, joint pain (arthralgia), and fever. While systemic lupus erythematosus (SLE) can affect various organs, including the heart, arrhythmia is not typically considered a primary or defining sign, symptom, or complication of drug-induced lupus or lupus-like syndrome, unlike the other options.

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Free Trivia FPGEE Exam Question and Answers