Lymphocytes are commonly stimulated in vitro by incubating them with specific antigens or mitogens to assess their proliferative response.
Lymphocyte stimulation assays are used to evaluate the functional capacity of lymphocytes and diagnose immunodeficiencies.
Mitogens are substances that stimulate lymphocyte proliferation, which is useful in assays to assess lymphocyte function.
Interleukin-2 (IL-2) is a cytokine produced by activated lymphocytes and is often measured to evaluate the extent of lymphocyte activation.
A lymphocyte proliferation test measures the capacity of lymphocytes to divide and proliferate in response to stimulation.
Lymphocyte stimulation assays are useful in monitoring the efficacy of immunotherapy, as they can show how well lymphocytes are responding to treatment.
B cells are responsible for producing antibodies that neutralize pathogens.
Lymphocyte stimulation assays can help predict organ rejection by assessing the recipient's immune response to donor antigens.
A poor lymphocyte response in a stimulation assay may indicate an immunodeficiency, where the immune system's ability to fight infections is compromised
A high level of lymphocyte activation generally indicates an effective immune response to pathogens or other immune challenges.
Lymphocytes are a type of white blood cell that plays a critical role in the immune response by fighting infections and providing immunity.