Free ISMP Safe Medication Principles Questions and Answers

Question 1

The ________ is the earliest and most sensitive indication of an acute malignant hyperthermia crisis.

Accepted Answer

An increase in end-tidal carbon dioxide

Answer

An increase in end-tidal carbon dioxide (ETCO2) is recognized as the earliest and most sensitive indicator of an acute malignant hyperthermia (MH) crisis. MH is a rare but life-threatening reaction to certain anesthetic agents. The sudden, unexplained rise in ETCO2 reflects the hypermetabolic state and increased CO2 production characteristic of MH, often occurring before a significant rise in body temperature.

Question 2

Which medication do you take in a mental health crisis?

Accepted Answer

Dantrolene

Answer

Dantrolene is the specific medication used to treat malignant hyperthermia (MH), a severe and potentially fatal reaction that can occur during or after certain types of anesthesia. It works by interfering with calcium release from the sarcoplasmic reticulum in muscle cells, thereby reducing the muscle rigidity and hypermetabolism associated with MH. Ryanodex, Dantrium, and Revonto are different formulations or brand names of dantrolene.

Question 3

What are the two acceptable methods for destroying controlled narcotics, according to the DEA?

Accepted Answer

incineration or chemical digestion

Answer

The DEA has strict regulations for the destruction of controlled narcotics to prevent diversion and abuse. The two acceptable methods for rendering controlled substances non-retrievable and unusable are incineration (burning at a high temperature) or chemical digestion. Other methods like flushing or placing in trash with coffee grounds/kitty litter are generally not compliant for controlled substances in healthcare settings.

Question 4

All of these are effective strategies to prevent the abuse of substances that sound alike and look alike (SALAD), with the exception of

Accepted Answer

identifying SALAD on your facility's printed formulary

Answer

Identifying SALAD (Sound-Alike, Look-Alike Drug) medications solely on a facility's *printed* formulary is generally not an effective standalone strategy to prevent errors. This method doesn't actively prevent selection errors at the point of prescribing or dispensing. Effective strategies involve active barriers like physical separation, using visual alerts (stickers), and referencing comprehensive lists from organizations like ISMP to directly mitigate confusion during medication processes.

Question 5

Reconstituted vancomycin 1 gram vials require 20 ml of sterile water for injection. How many ml are required after reconstituting with the SWFI for a dose of 750 mg?

Accepted Answer

15 ml

Answer

To solve this, first calculate the concentration of the reconstituted vancomycin. 1 gram (1000 mg) dissolved in 20 ml yields a concentration of 1000 mg / 20 ml = 50 mg/ml. To determine the volume needed for a 750 mg dose, divide the desired dose by the concentration: 750 mg / (50 mg/ml) = 15 ml. Therefore, 15 ml is required for a 750 mg dose.

ISMP - Institute for Safe Medication Practices Practice Test

ISMP - Institute for Safe Medication Practices Practice Test

Free ISMP Safe Medication Principles Questions and Answers