38-year-old Mike Smith, a man with diabetes mellitus, has been receiving hemodialysis for two years. The partner of Mike Smith reports that he has become more aloof and uninterested, napping for most of the day. <br>
Question: To manage his depression, Mike Smith has begun taking fluoxetine 20 mg daily, an SSRI. The patient claims no improvement after two weeks. The patient needs to be informed that:
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A
SSRIs may be ineffective for the patient
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B
A different SSRI may be needed
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C
The patient may respond better to other types of therapy
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D
Four to six weeks are needed to evaluate response