Please select 3 correct answers
A. Add Empagliflozin: Empagliflozin (SGLT2 inhibitor) is appropriate as the patient has uncontrolled A1C > 7.0% and has cardiovascular benefits for patients with diabetes and hypertension.
B. Increase Lisinopril: Blood pressure (138/88 mmHg) exceeds the target for diabetes (<130/80 mmHg per ACC/AHA guidelines). Titrating Lisinopril to 20 mg is appropriate.
C. Start Atorvastatin: For patients with diabetes aged 40-75 years, moderate- to high-intensity statin therapy is recommended regardless of LDL level. Atorvastatin 20 mg aligns with this.
D. Add Aspirin: While Aspirin is beneficial for secondary prevention, there’s insufficient evidence for primary prevention unless additional risk factors exist.
E. Continue current therapy: Inappropriate given his elevated A1C, blood pressure, and LDL.
Statin intolerance: Muscle symptoms are common with Simvastatin. Switching to a lower dose, less lipophilic statin like Atorvastatin can reduce side effects while maintaining LDL reduction.
A. Reducing Simvastatin: May not adequately address LDL goals.
C. Coenzyme Q10: Not evidence-based for muscle symptoms.
D. Continue therapy: Inappropriate since symptoms warrant action.
Hyperkalemia: Lisinopril (ACE inhibitor) can cause elevated potassium. Potassium at 5.4 mEq/L exceeds safe limits, so temporarily holding Lisinopril is appropriate.
A. Increase Lisinopril: Contraindicated with hyperkalemia.
B. Switch to Sacubitril/Valsartan: Not appropriate until potassium is normalized.
C. Start Spironolactone: Spironolactone can further increase potassium and is unsafe here.
ICS/LABA combination: Recommended for COPD patients with frequent exacerbations despite long-acting bronchodilator therapy (Tiotropium). Fluticasone/Salmeterol is an appropriate choice.
B. Theophylline: Rarely used due to side effects and drug interactions.
C. Increase Albuterol: Overuse does not address the need for maintenance therapy.
D. Roflumilast: Reserved for severe COPD with chronic bronchitis.
Please select 3 correct answers
A. DASH diet: Proven to significantly reduce blood pressure.
B. Weight loss: Even 5-10% body weight reduction can lower blood pressure.
C. Sodium restriction: Limiting sodium to <2400 mg/day helps reduce hypertension.
D. Increase caffeine: Caffeine can transiently increase BP and is inappropriate.
E. Resistance exercise: Beneficial, but aerobic exercise (not resistance) has the strongest BP-lowering effect.