Free Bachelor of Pharmacy (B.Pharm.) Biochemistry Questions and Answers

Question 1

Proteins' peptide bonds are detected by

Accepted Answer

Biuret test

Answer

The Biuret test is a specific chemical test used to detect the presence of peptide bonds, which are the characteristic linkages between amino acids in proteins. The test relies on the reaction of copper(II) ions in an alkaline solution with the peptide bonds, producing a distinctive violet color. This color change indicates the presence of proteins or peptides containing at least two peptide bonds.

Question 2

Which amino acid is the smallest?

Accepted Answer

Glycine

Answer

Glycine is the smallest and simplest amino acid because its side chain (R-group) consists of a single hydrogen atom. This unique structure makes it the only achiral (non-chiral) amino acid among the standard 20, contributing to its flexibility and specific roles in protein structure and function.

Question 3

Related to vitamin A are:

Accepted Answer

β-ionone

Answer

Vitamin A (retinol) and its precursors, such as beta-carotene, are structurally derived from β-ionone. The β-ionone ring is a crucial structural component found in beta-carotene, which is then cleaved to form retinal, a direct precursor to vitamin A. This specific ring structure is essential for the biological activity and function of vitamin A in the body.

Question 4

The following vitamins interact with Ca++ ATPase in intestinal cells:

Accepted Answer

Vitamin D

Answer

Vitamin D plays a critical role in regulating calcium absorption in the intestines. It stimulates the synthesis of calcium-binding proteins and enhances the activity of Ca++ ATPase, an enzyme responsible for actively transporting calcium ions across intestinal cell membranes into the bloodstream. This action is vital for maintaining proper calcium levels and bone health.

Question 5

Regular use of the antitubercular medication isoniazid results in deficiencies of:

Accepted Answer

vitamin B6

Answer

Isoniazid, an antitubercular medication, is known to interfere with the metabolism of vitamin B6 (pyridoxine). It forms an inactive derivative with pyridoxal phosphate, the active form of vitamin B6, leading to its depletion in the body. This deficiency can cause peripheral neuropathy, a common side effect of isoniazid therapy, which is often prevented by co-administering vitamin B6 supplements.

B.Pharm. Bachelor of Pharmacy Practice Test

B.Pharm. Bachelor of Pharmacy Practice Test

Free Bachelor of Pharmacy (B.Pharm.) Biochemistry Questions and Answers