American Board of Psychiatry and Neurology

FREE ABPN Basic Questions And Answers

Which of the following descriptions of Neurontin, or gabapentin is NOT TRUE?

Renal adjustment is required

Titration- Day 1- 300mg at bedtime; Day 2- 300mg BiD; Day 3- 300mg TiD

Common ADE- Dizziness, somnolence

Onset of action = 2-3 weeks, Trial requires = 3-8 weeks

All of the above.

Correct! Wrong!

Explanation:
The above statements are true. Gabapentin requires renal adjustment; its onset of effect is 2-3 weeks; its trial period is 3-8 weeks; and its titration plan is 300 mg at bedtime on day 1, 300 mg twice daily on day 2, and 300 mg three times daily on day 3.

Which of the following statements of the many forms of chronic pain is NOT TRUE?

Microvasculature vasoconstriction leads to diabetic neuropathy.

The "tingling" sensation is caused by neurons that have become hypersensitive as a result of demyelinated axons and changes in sodium receptor concentrations.

Only morphologic changes are observed in cases of chronic back pain.

Neuralgia postherpetic might persist for years.

All of the above.

Correct! Wrong!

Explanation:
It is possible to have chronic back pain without any morphologic changes.

Applying a 5% patch, which can be cut to fit the administration site, once a day is part of the proper lidocaine patch administration protocol.

True

False

Correct! Wrong!

Explanation:
Proper administration every 12 hours and the patch can be cut to fit the site.

Which of the following statements regarding Lyrica, or pregabalin is NOT TRUE?

Starting dose - 500mg/day; Titration-Within 1 week

Maximum dosages based on the indication

Requires renal adjustment

Patients at risk of cardiovascular disease should use this medication with caution since there is a possibility of peripheral edema.

All of the above.

Correct! Wrong!

Explanation:
The initial dosage is 75 mg BiD but you should have an idea within 10X the correct doses.

The CIWA-Ar score is used to determine how to treat sedative and hypnotic withdrawal, which is different from alcohol withdrawal.

True

False

Correct! Wrong!

Explanation:
The basis for treating sedatives and hypnotics is based on the agent of abuse. Alcohol has a 48–72 hour lag in delirium; sed/hyp may act more quickly).

Which of the tools listed below is used to evaluate how severe the symptoms of alcohol withdrawal are?

McGill

NIH Consensus Scale

CIWA-Ar

COWS

All of the above.

Correct! Wrong!

Explanation:
One tool for determining the severity of alcohol withdrawal symptoms is the Clinical Institute Withdrawal Assessment for Alcohol, updated, or CIWA-Ar. It is a standardized diagnostic tool that aids medical practitioners in assessing and tracking the symptoms that people going through alcohol withdrawal encounter.

Which of the following claims regarding alcohol's PK and PD is NOT TRUE?

Alcohol attaches itself to the GABA receptor's benzodiazepine site.

Long-term alcohol use causes glutamate hypersensitivity.

Prolonged open chloride ion channel times are the eventual result.

Alcohol dehydrogenase's downregulation causes acute toxicity.

All of the above.

Correct! Wrong!

Explanation:
Alcohol dehydrogenase downregulation is not the cause of alcohol's acute toxicity. Alcohol's depressive effects on the central nervous system are the main cause of acute toxicity, which can result in respiratory depression, decreased

Constipation is the pharmacologic side effect of opioid receptors (mu, kappa, and delta) based on the action of the delta receptor.

True

False

Correct! Wrong!

Explanation:
Pharmacology side effects of constipation are a result of action on the mu receptor.

Which of the following claims about Wernicke's Encephalopathy (WE) is NOT TRUE?

Although there are no set rules, it is preferable to use IV therapy with a continuous infusion of 2000 mg for more than 60 minutes.

WE is caused by a thiamine deficit brought on by alcohol misuse.

Characterized by neurological issues such as ataxia of the gait, disorientation, and ophthalmoplegia (impaired eye movement).

Korsakoff's Syndrome deteriorating is one of the complications of WE.

When WE is suspected, treatment should start immediately even before probable test findings.

Correct! Wrong!

Explanation:
For a brief treatment, IV is recommended: 500 mg IV/IM tid for three days, followed by 500 mg IV/IM daily for five days, then oral therapy if symptoms have improved.

Which of the following is NOT TRUE about tramadol?

Titrate up as tolerated

Lower chance of respiratory depression

Non-controlled substance

Epileptogenic risk

All of the above.

Correct! Wrong!

Explanation:
The maximum dosage is 400 mg/day.

By the use of the descending pain pathway, the dorsal horn facilitates the transmission of signals from peripheral nerves to the thalamus in response to noxious stimuli.

True

False

Correct! Wrong!

Explanation:
The ascending pain pathway is used to transmit pain from nerves to the thalamus through the dorsal horn, whereas the descending pain pathway (from the brain to the dorsal horn) uses signals to modify activity to control pain transmission.

FREE ABPN Basic Questions And Answers

Which of the following descriptions of Neurontin, or gabapentin is NOT TRUE?

Which of the following statements of the many forms of chronic pain is NOT TRUE?

Applying a 5% patch, which can be cut to fit the administration site, once a day is part of the proper lidocaine patch administration protocol.

Which of the following statements regarding Lyrica, or pregabalin is NOT TRUE?

The CIWA-Ar score is used to determine how to treat sedative and hypnotic withdrawal, which is different from alcohol withdrawal.

Which of the tools listed below is used to evaluate how severe the symptoms of alcohol withdrawal are?

Which of the following claims regarding alcohol's PK and PD is NOT TRUE?

Constipation is the pharmacologic side effect of opioid receptors (mu, kappa, and delta) based on the action of the delta receptor.

Which of the following claims about Wernicke's Encephalopathy (WE) is NOT TRUE?

Which of the following is NOT TRUE about tramadol?

By the use of the descending pain pathway, the dorsal horn facilitates the transmission of signals from peripheral nerves to the thalamus in response to noxious stimuli.

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