A patient with venous insufficiency has a wound that is not healing despite local wound care. The underlying systemic mechanism causing delayed healing is BEST described as:
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A
Arterial hypoperfusion causing tissue ischemia and necrosis
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B
Chronic venous hypertension leading to fibrin cuff formation and tissue hypoxia
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C
Lymphatic obstruction causing immune cell accumulation
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D
Venous thrombosis blocking growth factor delivery to wound