LPN Pharmacology & Medication Administration 2

Question 1

A patient is prescribed metformin 500 mg PO BID. Which condition is an absolute contraindication to this medication?

Accepted Answer

Renal impairment with GFR < 30 mL/min

Answer

Metformin is contraindicated in significant renal impairment (GFR < 30 mL/min) due to the risk of lactic acidosis.

Question 2

Which measurement is most important to assess BEFORE administering digoxin to a patient?

Accepted Answer

Apical pulse for one full minute

Answer

The apical pulse must be assessed for a full minute before digoxin administration; hold and notify the provider if it is below 60 bpm.

Question 3

A patient taking warfarin reports eating large amounts of leafy green vegetables. The LPN should anticipate which laboratory change?

Accepted Answer

Decreased INR

Answer

Vitamin K found in leafy greens antagonizes warfarin, decreasing its anticoagulant effect and lowering the INR.

Question 4

Which route of medication administration provides the fastest systemic onset of action?

Accepted Answer

Intravenous

Answer

Intravenous administration delivers medication directly into the bloodstream, providing immediate systemic effect.

Question 5

A patient receives 25 mg diphenhydramine IV. Which side effect should the LPN most anticipate?

Accepted Answer

Sedation and dry mouth

Answer

Diphenhydramine is a first-generation antihistamine with strong anticholinergic and CNS-depressant properties, commonly causing sedation and dry mouth.

(LPN) Certified Practical Nurse Practice Test

(LPN) Certified Practical Nurse Practice Test

LPN Pharmacology & Medication Administration 2