ACLS Advanced Cardiovascular Life Support Practice Practice Test

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The ACLS look up card is one of the most essential tools a healthcare provider can carry into a resuscitation scenario. Whether you are a nurse, paramedic, respiratory therapist, or physician preparing for certification, having a concise reference that consolidates algorithms, drug dosages, and rhythm recognition criteria into a single, scannable format can mean the difference between a confident intervention and a hesitant one. This guide is designed to serve as your digital acls reference card, walking you through every component you need to master before your exam and in clinical practice.

The ACLS look up card is one of the most essential tools a healthcare provider can carry into a resuscitation scenario. Whether you are a nurse, paramedic, respiratory therapist, or physician preparing for certification, having a concise reference that consolidates algorithms, drug dosages, and rhythm recognition criteria into a single, scannable format can mean the difference between a confident intervention and a hesitant one. This guide is designed to serve as your digital acls reference card, walking you through every component you need to master before your exam and in clinical practice.

The American Heart Association structures ACLS around a core set of algorithms that address the most life-threatening cardiac emergencies. These include the cardiac arrest algorithm for shockable and non-shockable rhythms, the post-cardiac arrest care protocol, the bradycardia and tachycardia algorithms, and the acute coronary syndrome pathway. Each algorithm follows a systematic approach โ€” assess, intervene, reassess โ€” and memorizing the sequence of steps, along with the specific medications and their doses at each decision point, is what separates providers who pass on the first attempt from those who need to retake the exam.

One of the biggest challenges candidates face is not understanding the concepts individually but integrating them under pressure. When a mock patient goes into ventricular fibrillation, you must simultaneously recall the correct energy setting for defibrillation (120โ€“200 joules biphasic), the timing of CPR cycles (2 minutes between shocks), the first-line medication (epinephrine 1 mg IV/IO every 3โ€“5 minutes), and when to introduce amiodarone or lidocaine. A well-organized ACLS look up card gives you the structure to rehearse these pathways until the sequence becomes automatic muscle memory rather than anxious recollection.

Drug pharmacology is another high-yield area where reference cards shine. ACLS pharmacology covers more than a dozen medications โ€” adenosine, amiodarone, atropine, epinephrine, lidocaine, magnesium sulfate, dopamine, and more โ€” each with specific indications, dosing windows, routes of administration, and contraindications. Candidates who rely solely on narrative textbook descriptions often struggle to recall exact milligram values under timed exam conditions. Breaking pharmacology down into a table format, organized by drug class and indication, dramatically improves both retention and recall speed during high-stakes testing.

ECG rhythm recognition is the third pillar of ACLS mastery. You must be able to identify sinus bradycardia, sinus tachycardia, atrial fibrillation, atrial flutter, supraventricular tachycardia, ventricular tachycardia, ventricular fibrillation, pulseless electrical activity, and asystole โ€” not in a quiet classroom with unlimited time, but within seconds of seeing a rhythm strip during a megacode station. Pairing rhythm characteristics (rate, regularity, P-wave morphology, PR interval, QRS width) with their corresponding algorithm pathway is a core function of any effective reference card and a skill extensively tested on the written and skills evaluations.

Beyond the exam itself, the ACLS look up card has ongoing clinical value. Emergency departments, ICUs, code teams, and rapid response teams frequently post laminated algorithm reference cards at resuscitation stations precisely because even experienced providers benefit from a quick visual confirmation of the next step. Studies on clinical decision-making under stress consistently show that standardized cognitive aids reduce errors during resuscitation events, which is exactly why the AHA designs its algorithms to be both memorized and referenced. This guide will help you build both the knowledge and the reference habits that lead to certification success and better patient outcomes.

Throughout this article you will find algorithm breakdowns organized by emergency type, pharmacology tables sorted by drug class, rhythm recognition tips, study schedule guidance, and a comprehensive FAQ section addressing the questions that ACLS candidates ask most frequently. Whether you are approaching your initial certification or gearing up for renewal, the structured reference material here will help you walk into exam day with clarity, confidence, and command of every algorithm the AHA will test you on.

ACLS Certification by the Numbers

๐Ÿ“‹
8+
Core ACLS Algorithms
๐Ÿ’Š
12+
High-Yield Drugs to Know
๐Ÿ†
~80%
First-Attempt Pass Rate
โฑ๏ธ
2 min
CPR Cycle Between Shocks
๐ŸŽ“
2 years
Certification Validity
Test Your ACLS Look Up Card Knowledge โ€” Free Practice Quiz

Understanding the cardiac arrest algorithms in depth is the foundation of any effective ACLS study plan. The shockable rhythm pathway โ€” covering ventricular fibrillation and pulseless ventricular tachycardia โ€” begins with immediate high-quality CPR and rapid defibrillation. The energy dose for the first shock is 120โ€“200 joules on a biphasic defibrillator, though providers should use the device manufacturer's recommended setting when available. After the shock, CPR resumes immediately for a full 2-minute cycle before a rhythm check, a discipline that prevents the common error of pausing compressions prematurely to look at the monitor.

Epinephrine is introduced into the shockable arrest pathway after the second shock, dosed at 1 mg IV or IO, and repeated every 3โ€“5 minutes. It is critical to know that epinephrine administration should not interrupt CPR cycles โ€” it is given during compressions, not during rhythm checks or shock delivery.

Amiodarone enters the algorithm after the third shock, with a first dose of 300 mg IV/IO bolus, followed by a second dose of 150 mg if the rhythm remains refractory. Lidocaine is an acceptable alternative at 1โ€“1.5 mg/kg IV for the first dose, with subsequent doses of 0.5โ€“0.75 mg/kg at 5โ€“10 minute intervals up to a maximum of 3 mg/kg.

The non-shockable pathway โ€” covering pulseless electrical activity and asystole โ€” follows a different but equally systematic sequence. CPR continues without defibrillation, and epinephrine 1 mg IV/IO is given as soon as IV or IO access is established, with repeat dosing every 3โ€“5 minutes. The critical cognitive task in PEA is identifying and treating reversible causes, summarized by the Hs and Ts: hypovolemia, hypoxia, hydrogen ion excess (acidosis), hypo/hyperkalemia, hypothermia, tension pneumothorax, tamponade, toxins, thrombosis pulmonary, and thrombosis coronary. This list appears on every ACLS reference card and is consistently tested on the written examination.

Post-cardiac arrest care is a domain that has grown significantly in the updated AHA guidelines and is now weighted heavily in certification testing. Following return of spontaneous circulation (ROSC), priorities shift to optimizing oxygenation (target SpO2 of 92โ€“98%), ventilation (target PaCO2 of 35โ€“45 mmHg), and hemodynamic stability (target systolic blood pressure above 90 mmHg). Targeted temperature management between 32 and 36 degrees Celsius is recommended for comatose survivors, maintained for at least 24 hours. Coronary angiography is recommended for STEMI patients and should be considered for hemodynamically unstable patients regardless of whether STEMI is present on the initial ECG.

The ACS algorithm is another high-yield section of the ACLS look up card that receives dedicated attention in the certification exam. Initial management follows the MONA mnemonic โ€” morphine (used selectively), oxygen (only if SpO2 below 90%), nitroglycerin (sublingual or IV), and aspirin 162โ€“325 mg chewed.

A 12-lead ECG should be obtained within 10 minutes of patient contact, and the critical decision point is whether STEMI is present. If yes, the reperfusion strategy must be determined: primary percutaneous coronary intervention (PCI) is preferred if the door-to-balloon time can be achieved within 90 minutes; fibrinolytics are the alternative when PCI is not timely.

The bradycardia algorithm is triggered when the heart rate falls below 50 beats per minute and the patient displays signs or symptoms of hemodynamic compromise โ€” hypotension, altered mental status, chest pain, or signs of shock. Atropine 0.5 mg IV is the first-line intervention, repeatable every 3โ€“5 minutes to a maximum total dose of 3 mg.

If atropine is ineffective or the bradycardia is thought to be related to a high-degree AV block or infranodal block (where atropine would be contraindicated or ineffective), transcutaneous pacing should be initiated immediately. Dopamine infusion at 2โ€“20 mcg/kg/min or epinephrine infusion at 2โ€“10 mcg/min are the pharmacologic bridges while preparing for transvenous pacing.

The tachycardia algorithm is perhaps the most branching pathway in ACLS, requiring providers to simultaneously assess stability, classify the QRS as narrow or wide, and determine regularity. Unstable tachycardia โ€” defined by hypotension, altered consciousness, signs of shock, or ischemic chest discomfort โ€” is treated with immediate synchronized cardioversion regardless of the specific rhythm.

Stable tachycardia management diverges based on QRS width: narrow-complex rhythms are addressed with vagal maneuvers and adenosine first, while wide-complex rhythms of uncertain type are treated with adenosine if regular and monomorphic, or with amiodarone if the etiology is unclear. Torsades de pointes with a wide, polymorphic QRS and prolonged QT interval is specifically treated with magnesium sulfate 1โ€“2 g IV bolus.

ACLS ACLS Cardiac Rhythms & ECG Interpretation
Practice identifying VF, VT, SVT, and all ACLS-tested rhythms with timed questions
ACLS ACLS Cardiac Rhythms & ECG Interpretation 2
Advanced rhythm strips including AV blocks, wide-complex tachycardias, and artifact

ACLS Drug Reference: Key Medications by Category

๐Ÿ“‹ Arrest Medications

Epinephrine 1 mg IV/IO every 3โ€“5 minutes is the cornerstone pharmacologic intervention in both shockable and non-shockable cardiac arrest. It works by increasing systemic vascular resistance and coronary perfusion pressure, improving the likelihood of defibrillation success and ROSC. Amiodarone is the preferred antiarrhythmic for shock-refractory ventricular fibrillation and pulseless VT, given as 300 mg IV/IO for the first dose, followed by 150 mg if needed. Lidocaine serves as the alternative antiarrhythmic at 1โ€“1.5 mg/kg, with additional doses possible up to 3 mg/kg total cumulative dose.

Magnesium sulfate 1โ€“2 g IV/IO is specifically indicated for torsades de pointes, a polymorphic ventricular tachycardia associated with prolonged QT interval that does not respond to standard antiarrhythmics. Sodium bicarbonate is not routinely recommended in cardiac arrest but may be given for specific indications including severe hyperkalemia, tricyclic antidepressant overdose, or pre-existing metabolic acidosis. Calcium chloride 500โ€“1000 mg IV is indicated for hyperkalemia, hypocalcemia, and calcium channel blocker toxicity. These drug-indication pairs are classic exam questions, so pairing each medication with its specific clinical scenario is essential reference card knowledge.

๐Ÿ“‹ Rate & Rhythm Drugs

Adenosine is the first-line pharmacologic treatment for stable narrow-complex supraventricular tachycardia when vagal maneuvers have failed. The initial dose is 6 mg given as a rapid IV push through a large-bore antecubital vein, immediately followed by a 20 mL normal saline flush to ensure delivery to central circulation before the drug is metabolized. If the first dose fails to terminate the SVT, a second dose of 12 mg is given, and a third dose of 12 mg is an option. Adenosine has an extremely short half-life of about 10 seconds, which makes the rapid push and flush technique critically important for clinical effectiveness.

Atropine 0.5 mg IV is the first-line agent for symptomatic bradycardia, with a maximum cumulative dose of 3 mg. Smaller doses below 0.5 mg can paradoxically worsen bradycardia through a central vagal effect and should be avoided. For rate control in stable tachyarrhythmias including atrial fibrillation and flutter, beta-blockers such as metoprolol and calcium channel blockers such as diltiazem are the preferred agents. Amiodarone 150 mg IV over 10 minutes is used for stable wide-complex tachycardia of uncertain origin, making the amiodarone dosing distinction โ€” 300 mg bolus for arrest versus 150 mg over 10 minutes for stable tachycardia โ€” a high-frequency exam distinction that candidates must memorize precisely.

๐Ÿ“‹ Vasopressors & Infusions

Dopamine is the preferred vasopressor infusion for symptomatic bradycardia refractory to atropine, dosed at 2โ€“20 mcg/kg/min and titrated to hemodynamic response. At low doses (2โ€“5 mcg/kg/min) dopamine acts primarily on dopaminergic receptors, producing renal and splanchnic vasodilation; at moderate doses (5โ€“10 mcg/kg/min) it adds beta-1 adrenergic effects increasing heart rate and contractility; at high doses (10โ€“20 mcg/kg/min) alpha-1 effects dominate, causing vasoconstriction. Epinephrine infusion at 2โ€“10 mcg/min is an alternative to dopamine for bradycardia and is preferred in the post-arrest period when vasopressor support is needed alongside chronotropic effects.

Norepinephrine infusion at 0.1โ€“0.5 mcg/kg/min is used primarily for vasodilatory shock and hypotension in the post-arrest care period when blood pressure support is needed without significant chronotropy. Vasopressin, previously included in the AHA algorithm as an alternative to epinephrine in cardiac arrest at 40 units IV, was removed from the main algorithm in the 2015 guidelines update due to lack of evidence for superior outcomes, though some providers and institutions continue to use it. Understanding which medications are currently in versus out of the algorithm is an important detail for candidates using reference cards based on older editions, as guidelines do change across certification cycles.

Paper Reference Card vs. Digital ACLS Study Tools: Which Works Better?

Pros

  • Physical cards can be posted at workstations, on simulation mannequins, or in clinical areas for immediate visual reference during practice
  • No screen or battery required โ€” works in any environment including simulation labs, clinical units, and low-resource settings
  • Writing information by hand onto a physical card reinforces memory encoding through kinesthetic learning
  • Laminated cards are durable and can withstand clinical environments without risk of damage from fluids or gloves
  • Quick to scan at a glance โ€” a well-designed one-page card shows all algorithms simultaneously without scrolling
  • Can be customized with personal annotations, color-coding, and mnemonics that match your individual learning style

Cons

  • Physical cards become outdated when AHA guidelines are updated and must be replaced or corrected manually
  • Limited space forces trade-offs โ€” a wallet card cannot include every nuance of every algorithm without becoming unreadable
  • Cannot include interactive practice questions, rhythm strip videos, or self-testing features that digital tools provide
  • Easy to misplace, leave at home, or forget to bring to the exam review session when you need it most
  • Static format means you cannot quickly search for a specific drug or algorithm by keyword as you can on a digital platform
  • Does not provide performance tracking or analytics to identify which algorithm sections need more focused review time
ACLS ACLS Cardiac Rhythms & ECG Interpretation 3
Master complex rhythm scenarios including pulseless rhythms and post-arrest ECG changes
ACLS ACLS Pharmacology & Medications
Test drug doses, indications, contraindications, and timing for all ACLS medications

ACLS Reference Card Mastery Checklist

Memorize the 5-step shockable VF/pVT algorithm including defibrillation energy, epinephrine timing, and amiodarone doses
Learn the non-shockable PEA/asystole pathway and recite all 10 Hs and Ts reversible causes from memory
Drill the bradycardia algorithm sequence: atropine โ†’ transcutaneous pacing โ†’ dopamine/epinephrine infusion
Master the tachycardia algorithm branch points: stable vs. unstable, narrow vs. wide, regular vs. irregular
Identify all 9 ACLS-tested ECG rhythms within 10 seconds of seeing a rhythm strip
Recite adenosine dosing sequence: 6 mg โ†’ 12 mg โ†’ 12 mg, with rapid push and 20 mL flush technique
Distinguish amiodarone dosing for cardiac arrest (300 mg bolus) vs. stable tachycardia (150 mg over 10 min)
Know post-ROSC targets: SpO2 92โ€“98%, PaCO2 35โ€“45 mmHg, SBP above 90 mmHg, temp 32โ€“36ยฐC for 24 hours
Complete at least two full megacode simulations covering all algorithm branches under timed conditions
Pass three consecutive timed practice tests with scores above 84% before scheduling the certification exam
The Most Commonly Missed Reference Card Detail

Most exam failures trace back to one specific error: confusing the timing rules for epinephrine administration. Epinephrine 1 mg is given every 3โ€“5 minutes โ€” not every 2 minutes, which is the CPR cycle time. During a megacode, providers who give epinephrine every CPR cycle instead of every other cycle will demonstrate incorrect technique. Build the rhythm into your mental model: shock, 2 min CPR with epi, shock, 2 min CPR, shock, 2 min CPR with epi again. That pattern is what examiners look for.

ECG rhythm recognition is tested both on the written examination and during the practical megacode skills evaluation, making it one of the highest-leverage study areas for any candidate using an ACLS reference card. The ability to classify a rhythm correctly within seconds depends on a systematic four-step analysis: rate, regularity, P-wave presence and morphology, and QRS duration. Applying this framework consistently to every rhythm strip you encounter during study โ€” rather than pattern-matching at a glance โ€” builds the neural pathways needed for accurate identification under exam pressure.

Ventricular fibrillation is characterized by chaotic, disorganized electrical activity with no discernible P waves, QRS complexes, or T waves. The baseline is grossly irregular with variable amplitude, and there is no organized rhythm of any kind. Coarse VF (large amplitude deflections) tends to respond better to defibrillation than fine VF (small amplitude deflections), though both are treated identically with the shockable algorithm.

Pulseless ventricular tachycardia displays a wide QRS (typically greater than 0.12 seconds), a rate above 100 bpm, and a regular or near-regular rhythm โ€” the key differentiator from VF is that organized electrical activity is present even though it is producing no effective cardiac output.

Atrial fibrillation is identified by the absence of distinct P waves replaced by chaotic fibrillatory baseline activity, and an irregularly irregular ventricular response. The ventricular rate in uncontrolled AFib can range from 60 to well over 150 bpm depending on AV nodal conduction.

Atrial flutter classically shows a regular sawtooth flutter wave pattern at approximately 300 bpm, with a ventricular response that is most commonly 150 bpm (2:1 block), though 3:1 and 4:1 ratios also occur. Distinguishing AFib from flutter on a rhythm strip is a common exam question โ€” the key is identifying whether the baseline activity between QRS complexes is chaotic (AFib) or organized and sawtooth (flutter).

Supraventricular tachycardia (SVT) encompasses a group of rhythms originating above the bundle of His, typically presenting with a narrow QRS and a rate between 150 and 250 bpm. The rhythm is usually regular, and P waves may be absent, buried in the QRS, or appearing immediately after the QRS as retrograde P waves.

AVNRT (atrioventricular nodal reentrant tachycardia) and AVRT (atrioventricular reentrant tachycardia) are the two most common subtypes, both responding to vagal maneuvers and adenosine when the patient is hemodynamically stable. Recognition of narrow-complex tachycardia as likely SVT versus sinus tachycardia (which has visible P waves before each QRS) is a critical distinction that drives algorithm selection.

Third-degree (complete) heart block presents with complete dissociation between atrial and ventricular activity. The P-P interval is regular, the R-R interval is regular, but P waves and QRS complexes march through each other with no relationship. The ventricular rate is typically slow (20โ€“40 bpm for infranodal escape or 40โ€“60 bpm for junctional escape), and the QRS may be narrow if the escape pacemaker is junctional or wide if it is ventricular.

This rhythm is a critical finding because atropine is relatively contraindicated in complete heart block โ€” the AV node does not respond to atropine in the setting of complete block, and transcutaneous pacing should be initiated promptly if the patient is symptomatic.

Pulseless electrical activity (PEA) is not a single rhythm but rather a clinical state in which organized electrical activity is present on the monitor but the heart is generating insufficient mechanical force to produce a detectable pulse. PEA rhythms can include sinus rhythm, sinus tachycardia, idioventricular rhythms, and others.

The critical exam skill is recognizing that rhythm organization on the monitor does not equal adequate perfusion โ€” always check for a pulse before assuming the patient is stable. The treatment imperative in PEA is immediate high-quality CPR, epinephrine, and systematic evaluation for reversible causes using the Hs and Ts framework discussed earlier.

Asystole presents as a nearly flat or minimally undulating baseline with no organized electrical activity. Before diagnosing asystole, providers should verify the rhythm in at least two leads, confirm that lead connections are secure, and increase the gain on the monitor โ€” a truly flat line in all leads is asystole, while a fine VF may appear flat in one lead but show oscillations in another.

This lead confirmation step is a tested protocol component. Asystole carries the poorest prognosis of all arrest rhythms, and the primary interventions are high-quality CPR, epinephrine, and addressing reversible causes โ€” there is no role for defibrillation in confirmed asystole.

The practical megacode evaluation is where all reference card knowledge is tested under realistic time pressure, and preparation for this skills component requires a fundamentally different study approach than written exam preparation. During a megacode, you will be assigned the role of team leader and expected to direct a simulated resuscitation, calling out interventions, managing the team, communicating clearly, and demonstrating correct algorithm sequence without prompting. The evaluator is watching not just for what you do but for how you do it โ€” team leadership, closed-loop communication, and confident decision-making under pressure are all assessed components.

The AHA ACLS course is structured around a provider manual, skill practice stations, and the culminating megacode evaluation. Written test questions are drawn from the provider manual content and typically number around 50 questions in the online pre-course exam format, with a passing score of 84% or higher required.

The skills stations evaluate rhythm recognition, electrical cardioversion technique, airway management, and the megacode team leadership scenario. Candidates who fail the written test can typically retest once; candidates who fail skills stations receive remediation before retesting. Understanding the specific pass/fail criteria for your course format helps you prioritize your preparation time effectively.

One study strategy that dramatically improves megacode performance is verbal rehearsal of algorithm decision trees. Rather than silently reading the algorithms, practice saying them aloud in the exact language you will use during the evaluation: "Rhythm check โ€” I see ventricular fibrillation. Resume CPR, charging to 200 joules. Everyone clear? Delivering shock. Resume CPR immediately. Someone establish IV access, we will give epinephrine 1 milligram as soon as access is confirmed." This verbalization rehearsal builds both the content recall and the communication fluency that distinguishes confident team leaders from hesitant ones during evaluation.

Simulation-based practice remains the gold standard for megacode preparation, but not everyone has access to high-fidelity simulation equipment. Effective alternatives include partnered verbal run-throughs using a printed scenario card, online simulation platforms that present branching rhythm and vital sign scenarios, and video reviews of ACLS megacode demonstrations. The AHA itself publishes supplemental video content, and many ACLS training centers offer practice megacode sessions as part of their renewal courses. If your course includes a precourse self-assessment, complete it honestly and use your results to identify algorithm sections that need additional focused review before the in-person skills day.

Time management during the written exam is another skill that candidates underestimate. ACLS written questions often involve clinical vignettes that require you to identify the rhythm, select the next intervention, choose the correct dose, or identify the contraindication โ€” sometimes in the same question. Candidates who read every answer choice carefully and eliminate clearly wrong options before selecting typically perform better than those who choose the first plausible answer. For pharmacology questions specifically, watch for distractors that present correct medications in incorrect doses or correct doses for the wrong indication, as these are the most common trap formats.

Many certification candidates benefit from using the reference card during the study phase as an active recall tool rather than a passive reading source. Cover the right column of a two-column drug table and try to recall the dose before revealing it. Cover the algorithm steps after the first intervention and try to recite the next three steps before checking.

This retrieval practice approach, supported by extensive cognitive science research, produces significantly stronger long-term retention than re-reading the same content repeatedly. The goal is not to recognize the correct answer when you see it but to generate it independently โ€” exactly what the megacode demands.

Pairing your reference card study with timed practice questions from platforms like PracticeTestGeeks gives you both the content reinforcement and the exam-format familiarity needed for a first-attempt pass. The practice questions here mirror the vignette style and content distribution of the actual written exam, covering the full range of algorithms, pharmacology, rhythm interpretation, and post-arrest care topics.

After each practice session, review every missed question carefully โ€” not just to learn the right answer, but to understand precisely why the answer you chose was wrong, which reveals the specific algorithm branch or drug detail that needs reinforcement in your reference card review.

Practice ACLS Pharmacology & Medication Questions Now

Exam day execution begins the night before with a deliberate wind-down routine rather than a last-minute cramming session. Candidates who study heavily until midnight before their certification course report higher anxiety and more working memory interference during evaluations than those who do a light 30-minute review of algorithm key points and then prioritize sleep. By the time you arrive for your certification course, your knowledge base is largely set โ€” the goal on exam day is to access what you already know clearly and confidently, not to learn new information in the final hours before testing.

Arrive at your ACLS course with your reference materials reviewed but not clutched. The provider manual is typically available during the written exam at some institutions, though not all โ€” confirm this policy with your training center in advance. For the megacode, having a solid mental algorithm framework is far more useful than trying to mentally flip through reference card images under pressure. If you have practiced the verbal algorithm rehearsal described earlier, you will find that the words come automatically when the scenario begins, freeing your cognitive bandwidth for team leadership and clinical judgment rather than basic content recall.

During the megacode, one of the most common team leader errors is failing to explicitly communicate role assignments at the outset. When the scenario begins, take two seconds to assign roles: designate who will do compressions, who will manage the airway, who will establish vascular access, and who will draw and administer medications. This explicit role assignment prevents the chaotic duplication of effort and missed interventions that evaluators frequently cite as a reason for remediation. It also demonstrates the systematic leadership approach that the AHA specifically trains and evaluates.

If you encounter a scenario event that surprises you โ€” an unexpected rhythm change, a medication complication, or a team member reporting a finding you did not anticipate โ€” pause for one focused second before responding. State what you observe: "I see the rhythm has changed to a wide-complex tachycardia at 180 beats per minute. Is the patient stable? Vital signs please." Then branch through the algorithm based on the answer. This structured pause-and-assess technique prevents the snap reactions that lead candidates to cardiovert a stable patient or withhold cardioversion from an unstable one.

After your certification course concludes, begin thinking about your renewal timeline immediately. ACLS certification is valid for two years, and the renewal process typically requires completion of a recertification course (which is shorter than the initial course but covers the same algorithm content) or completion of an online renewal module followed by a skills check.

Mark your expiration date in your calendar with a 90-day reminder, because many training centers fill quickly and last-minute renewal attempts frequently result in brief lapses in certification. Maintaining a current reference card file in a dedicated study folder makes the renewal process significantly faster than starting from scratch two years later.

The most important piece of final advice for any ACLS candidate is this: trust the system. The AHA algorithms are deliberately designed to be systematic, memorable, and executable under extreme stress. They exist precisely because expert resuscitators recognized that cognitive load during a cardiac arrest is enormous, and that a clear, pre-memorized decision tree produces better outcomes than individual improvisation.

Your job during both the exam and real resuscitations is to execute the algorithm faithfully, communicate clearly, and keep the team moving through the steps. Everything on the reference card serves that purpose โ€” and mastering it serves both your certification and your patients.

Continue building your knowledge and testing yourself regularly with the practice quizzes available throughout this guide. Each quiz session reinforces algorithm recall, sharpens rhythm recognition, and familiarizes you with the question formats and distractors you will encounter on exam day. Consistent, distributed practice over several weeks produces dramatically better retention than a single intensive weekend of studying, so start early, use your reference card actively, and approach the certification course with the confidence that comes from thorough, systematic preparation.

ACLS ACLS Pharmacology & Medications 2
Advanced drug questions covering infusion rates, contraindications, and special populations
ACLS ACLS Pharmacology & Medications 3
Final pharmacology challenge with complex clinical vignettes and multi-drug scenarios

ACLS Questions and Answers

What is an ACLS look up card and what should it include?

An ACLS look up card is a condensed reference document that organizes the key algorithms, drug doses, and rhythm criteria from the AHA ACLS guidelines into a format that can be quickly scanned during study or clinical practice. It should include the cardiac arrest algorithms for shockable and non-shockable rhythms, the bradycardia and tachycardia algorithms, post-ROSC care targets, the Hs and Ts of reversible causes, and a pharmacology table with doses for all core ACLS medications.

How is the ACLS written exam structured, and what score do I need to pass?

The ACLS written exam typically consists of approximately 50 multiple-choice questions drawn from the provider manual. Questions cover algorithm sequencing, rhythm recognition, pharmacology, and post-cardiac arrest care. A score of 84% or higher is required to pass, meaning you can miss no more than 8 questions on a 50-question exam. The exam may be administered online as a precourse self-assessment or in person at the training center, depending on the course format your institution offers.

What is the first medication given in a shockable cardiac arrest?

In a shockable cardiac arrest (VF or pulseless VT), the first pharmacologic intervention is epinephrine 1 mg IV or IO, given after the second defibrillation attempt. The first intervention overall is immediate defibrillation followed by 2 minutes of CPR. Epinephrine is repeated every 3โ€“5 minutes throughout the arrest. Amiodarone 300 mg IV/IO is added if the rhythm remains refractory after the third defibrillation attempt, making it the second class of drug introduced in the shockable algorithm.

What are the Hs and Ts in ACLS, and why are they important?

The Hs and Ts are a mnemonic for the reversible causes of cardiac arrest, particularly relevant in PEA and asystole. The 5 Hs are hypovolemia, hypoxia, hydrogen ion excess (acidosis), hypo/hyperkalemia, and hypothermia. The 5 Ts are tension pneumothorax, tamponade, toxins, thrombosis pulmonary, and thrombosis coronary. Identifying and treating a reversible cause during the arrest is the primary strategy for achieving ROSC in non-shockable rhythms, making this list a mandatory memorization item for every ACLS candidate.

How do I distinguish stable from unstable tachycardia in the ACLS algorithm?

Unstable tachycardia is defined by the presence of serious signs or symptoms directly caused by the rapid heart rate. These include hypotension (SBP below 90 mmHg), altered mental status or decreased level of consciousness, signs of poor perfusion such as cool and clammy skin, ischemic chest pain, or acute heart failure. If any of these are present and the rate is above 150 bpm, the patient is considered unstable and immediate synchronized cardioversion is indicated regardless of the specific rhythm type.

What is the correct adenosine dosing sequence for SVT?

For stable narrow-complex SVT unresponsive to vagal maneuvers, adenosine is given as a rapid IV push through a large-bore antecubital or more proximal vein, immediately followed by a 20 mL normal saline flush. The sequence is: first dose 6 mg rapid IV push, second dose 12 mg if the first dose does not terminate the SVT, and a third dose of 12 mg is an option if the second dose fails. The rapid push technique is essential because adenosine has a half-life of approximately 10 seconds and must reach central circulation before being metabolized.

Can I use reference materials during the ACLS exam?

Policy varies by training center and course format. Some institutions allow candidates to use the AHA provider manual during the written exam, treating it as an open-book assessment focused on applying knowledge rather than memorizing verbatim facts. Other centers administer the written exam without reference materials. The megacode skills evaluation is never open-reference โ€” you must demonstrate algorithm knowledge and team leadership without consulting notes. Confirm the specific policy with your training center before the course, and study accordingly.

What post-arrest targets should I know for the ACLS certification exam?

After return of spontaneous circulation, the AHA recommends targeting SpO2 of 92โ€“98% (avoid hyperoxia), PaCO2 of 35โ€“45 mmHg (avoid hyperventilation and hypoventilation), systolic blood pressure above 90 mmHg, mean arterial pressure above 65 mmHg, and blood glucose between 140โ€“180 mg/dL. Targeted temperature management between 32 and 36 degrees Celsius is recommended for comatose survivors, maintained for at least 24 hours. Coronary angiography is recommended for STEMI and should be considered for hemodynamically unstable post-arrest patients without STEMI.

How long is ACLS certification valid, and what does renewal involve?

ACLS certification issued by the AHA is valid for two years from the date of course completion. Renewal requires completing an ACLS recertification course, which is shorter than the initial certification course (typically a half-day) but covers the same algorithm content with an emphasis on updates and skills practice. Some institutions offer HeartCode ACLS online renewal followed by a skills check. It is advisable to schedule renewal at least 90 days before expiration, as training center availability can be limited in high-demand areas.

What is the difference between synchronized cardioversion and defibrillation in ACLS?

Defibrillation delivers an unsynchronized shock at any point in the cardiac cycle and is used exclusively for pulseless rhythms โ€” ventricular fibrillation and pulseless ventricular tachycardia. Synchronized cardioversion delivers a shock timed to the R wave of the QRS complex to avoid the vulnerable T-wave period, preventing the shock from triggering VF in a patient who still has cardiac output. Synchronized cardioversion is used for unstable tachycardias with a pulse, including SVT, atrial flutter, atrial fibrillation, and stable monomorphic VT. Never synchronize for VF โ€” the device may fail to detect R waves and delay delivery indefinitely.
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