AMC MCQ Study Guide 2026

Everything you need to pass the AMC MCQ exam in one place: the exam format, every topic to study, real practice questions with explanations, flashcards, and full-length practice tests. Free, no sign-up needed.

📋 AMC MCQ Exam Format at a Glance

150

Questions

210 min

Time Limit

50%

Passing Score

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📚 AMC MCQ Topics to Study (69)

Practice Test · 25 cards Cardiovascular Medicine · 7 cards Cardiovascular Medicine · 7 cards Cardiovascular Medicine · 7 cards Cardiovascular Medicine · 7 cards Ethics and Professional Practice · 7 cards Ethics and Professional Practice · 7 cards Ethics and Professional Practice · 7 cards Ethics and Professional Practice · 7 cards Gastroenterology and Surgery · 7 cards Gastroenterology and Surgery · 7 cards Gastroenterology and Surgery · 7 cards Gastroenterology and Surgery · 7 cards General Surgery Principles · 7 cards General Surgery Principles · 7 cards General Surgery Principles · 7 cards General Surgery Principles · 7 cards Musculoskeletal and Dermatology · 7 cards Musculoskeletal and Dermatology · 7 cards Musculoskeletal and Dermatology · 7 cards Musculoskeletal and Dermatology · 7 cards Neurology and Mental Health · 7 cards Neurology and Mental Health · 7 cards Neurology and Mental Health · 7 cards Neurology and Mental Health · 7 cards Obstetrics and Gynaecology · 7 cards Obstetrics and Gynaecology · 7 cards Obstetrics and Gynaecology · 7 cards Obstetrics and Gynaecology · 7 cards Ophthalmology and ENT · 7 cards

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✍️ Sample AMC MCQ Questions & Answers

1. A 55-year-old woman with rheumatoid arthritis on long-term NSAIDs develops a rising creatinine, sterile pyuria, eosinophiluria and a rash. What is the most likely renal diagnosis?

✓ Acute interstitial nephritis

Drug-induced acute interstitial nephritis classically presents with rash, eosinophiluria and rising creatinine.

2. A 70-year-old woman has a new headache, scalp tenderness, jaw claudication and a raised ESR. What is the most appropriate immediate management?

✓ Start high-dose corticosteroids immediately

Suspected giant cell arteritis requires immediate corticosteroids to prevent irreversible blindness, without waiting for biopsy.

3. A 32-year-old woman with depression on a high-dose SSRI is started on tramadol and develops agitation, clonus, hyperreflexia, tremor and fever. What is the most likely diagnosis?

✓ Serotonin syndrome

Clonus, hyperreflexia and agitation after adding a serotonergic drug indicate serotonin syndrome.

4. A 38-year-old with recurrent sinusitis presents with nasal polyps, bronchial asthma, and develops bronchospasm after taking aspirin for a headache. What is this triad called?

✓ Samter's triad (aspirin-exacerbated respiratory disease)

Samter's triad (aspirin-exacerbated respiratory disease) consists of asthma, nasal polyps, and aspirin/NSAID sensitivity caused by aberrant arachidonic acid metabolism.

5. In the WHO surgical safety checklist, when is the 'time out' performed?

✓ Before skin incision

The 'time out' occurs immediately before incision to confirm patient, site and procedure.

6. A patient with chronic myeloid leukaemia (CML) is found to have the Philadelphia chromosome t(9;22). Which molecular target does imatinib inhibit?

✓ BCR-ABL tyrosine kinase

Imatinib is a selective BCR-ABL tyrosine kinase inhibitor that blocks the constitutively active kinase produced by the Philadelphia chromosome translocation in CML.

🎯 Free AMC MCQ Practice Tests

Practice Test · 25 questions Ophthalmology and ENT · 7 questions Neurology and Mental Health · 7 questions Neurology and Mental Health · 7 questions Neurology and Mental Health · 7 questions Neurology and Mental Health · 7 questions Ophthalmology and ENT · 7 questions Renal and Endocrine Disorders · 7 questions Renal and Endocrine Disorders · 7 questions Ophthalmology and ENT · 7 questions

📖 AMC MCQ Guides & Articles

Your AMC MCQ Study Path

1. Learn with Flashcards → 2. Drill Practice Tests → 3. Take the Full Exam Simulation

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