Musculoskeletal and Dermatology Flashcards
7 cards from real AMC MCQ practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.
Read the first 7 Musculoskeletal and Dermatology flashcards as text
A 55-year-old man presents with sudden severe pain, redness and swelling of the first metatarsophalangeal joint. What is the most likely diagnosis?
Answer: Acute gout
Acute podagra of the first MTP joint with rapid onset is classic for gout.
Which investigation is most useful to confirm a diagnosis of gout in a swollen joint?
Answer: Joint aspiration with polarised microscopy
Negatively birefringent needle-shaped urate crystals on aspirate confirm gout.
A 30-year-old woman has symmetrical pain and stiffness of the small joints of both hands, worse in the morning for over an hour. What is the most likely diagnosis?
Answer: Rheumatoid arthritis
Symmetrical small-joint involvement with prolonged morning stiffness suggests rheumatoid arthritis.
Which antibody is most specific for rheumatoid arthritis?
Answer: Anti-cyclic citrullinated peptide (anti-CCP)
Anti-CCP antibodies are highly specific for rheumatoid arthritis.
A child presents with a salmon-pink, erythematous rash, high spiking fevers and arthritis. Which condition is most likely?
Answer: Systemic juvenile idiopathic arthritis
Spiking fevers with an evanescent salmon-pink rash and arthritis indicate systemic JIA (Still disease).
Which skin finding is characteristic of dermatomyositis?
Answer: Heliotrope rash on the eyelids
A violaceous heliotrope rash over the eyelids is a hallmark of dermatomyositis.
A 70-year-old woman presents with bilateral shoulder and hip girdle pain and stiffness, with a markedly raised ESR. What is the most likely diagnosis?
Answer: Polymyalgia rheumatica
Proximal girdle stiffness with high ESR in an elderly patient suggests polymyalgia rheumatica.