CPHON Pediatric Hematology Oncology Nurse 3

Question 1

Which chemotherapy agent is most associated with hemorrhagic cystitis in pediatric patients?

Accepted Answer

Cyclophosphamide

Answer

Cyclophosphamide is metabolized to acrolein, which irritates the bladder lining causing hemorrhagic cystitis; mesna and hydration are used for prevention.

Question 2

A child with neuroblastoma is scheduled for a MIBG scan. Which medication must be given before the procedure?

Accepted Answer

Potassium iodide to protect the thyroid

Answer

Potassium iodide (or Lugol's solution) is given before MIBG scans to block thyroid uptake of radioactive iodine.

Question 3

Which is the most appropriate nursing intervention for a child experiencing vincristine-induced constipation?

Accepted Answer

Prophylactic bowel regimen with stimulant laxatives started at initiation of vincristine

Answer

Vincristine causes autonomic neuropathy leading to constipation; a prophylactic bowel regimen is standard practice from the start of therapy.

Question 4

A 12-year-old receiving asparaginase develops sudden severe abdominal pain with elevated lipase and amylase. The nurse should suspect:

Accepted Answer

Asparaginase-induced pancreatitis

Answer

Asparaginase is a well-known cause of pancreatitis in pediatric oncology patients, manifesting with abdominal pain and elevated pancreatic enzymes.

Question 5

The nurse is preparing to administer a platelet transfusion to a child with acute leukemia who previously had a severe transfusion reaction. Which product modification is most appropriate?

Accepted Answer

Leukoreduced and irradiated platelets

Answer

Leukoreduction reduces febrile reactions and CMV transmission, while irradiation prevents transfusion-associated graft-versus-host disease in immunocompromised patients.

CPHON Exam Practice Test

CPHON Exam Practice Test

CPHON Pediatric Hematology Oncology Nurse 3