CPHON Chemotherapy Administration and Safety

Question 1

Which personal protective equipment (PPE) is MOST important when administering intravenous vesicant chemotherapy to a pediatric patient?

Accepted Answer

Double gloves and a gown

Answer

Surgical mask only

Answer

Face shield only

Answer

Standard gloves only

Question 2

A child receiving vincristine develops jaw pain and peripheral tingling. The nurse recognizes these as signs of:

Accepted Answer

Peripheral neuropathy

Answer

Hypersensitivity reaction

Answer

Tumor lysis syndrome

Answer

Extravasation

Question 3

When preparing to administer intrathecal chemotherapy to a child, which action is MOST critical?

Accepted Answer

Verify the drug with a second licensed nurse

Answer

Use a 20-gauge needle

Answer

Warm the solution to body temperature

Answer

Administer via rapid IV push

Question 4

A nurse notices swelling and burning at a child's IV site during doxorubicin infusion. The FIRST action should be:

Accepted Answer

Stop the infusion immediately and disconnect the IV

Answer

Slow the infusion rate

Answer

Apply a warm compress

Answer

Flush the line with normal saline

Question 5

Which chemotherapy agent requires prehydration and mesna to prevent hemorrhagic cystitis?

Accepted Answer

Ifosfamide

Answer

Methotrexate

Answer

Cytarabine

Answer

L-asparaginase

Question 6

A child on high-dose methotrexate has a serum methotrexate level of 10 micromol/L at 24 hours. The nurse should anticipate administering:

Accepted Answer

Leucovorin rescue

Answer

Dexrazoxane

Answer

Rasburicase

Answer

Filgrastim