CPHON Chemotherapy Administration and Safety 3

Question 1

A nurse is priming IV tubing for a cisplatin infusion. Which solution is appropriate for this agent?

Accepted Answer

0.9% Normal Saline

Answer

Cisplatin must be administered in normal saline because dextrose-containing solutions can cause cisplatin degradation and precipitation.

Question 2

Which lab value is MOST important to monitor before each dose of cisplatin?

Accepted Answer

Serum creatinine

Answer

Cisplatin is nephrotoxic; serum creatinine must be checked before each dose because impaired renal function can cause dangerous drug accumulation.

Question 3

A child on cyclophosphamide therapy should be instructed to:

Accepted Answer

Void frequently and maintain high fluid intake

Answer

High fluid intake and frequent voiding flush acrolein metabolites from the bladder, reducing hemorrhagic cystitis risk.

Question 4

The nurse notes that a chemotherapy order includes the child's weight from 3 weeks ago. The BEST action is:

Accepted Answer

Obtain and document current weight before administering

Answer

Chemotherapy dosing is weight-based; pediatric patients can gain or lose weight rapidly, so current weight must be used.

Question 5

Which intervention BEST prevents central line-associated bloodstream infection (CLABSI) during chemotherapy administration?

Accepted Answer

Use strict aseptic technique with each line access

Answer

Strict aseptic technique during every central line access is the most effective intervention to prevent CLABSI in immunocompromised patients.

CPHON Exam Practice Test