ABPath Pathology 3

Question 1

A patient with chronic gastroesophageal reflux develops columnar epithelium with goblet cells in the distal esophagus. This is termed?

Accepted Answer

Barrett esophagus

Answer

Barrett esophagus is intestinal metaplasia of the esophageal lining, a risk factor for adenocarcinoma.

Question 2

Which cellular adaptation refers to an increase in the SIZE of individual cells, as seen in cardiac muscle under hypertension?

Accepted Answer

Hypertrophy

Answer

Hypertrophy is enlargement of cells; cardiac myocytes cannot divide so they enlarge.

Question 3

The presence of Auer rods in a bone marrow aspirate is diagnostic of which condition?

Accepted Answer

Acute myeloid leukemia

Answer

Auer rods are needle-like azurophilic granules found in myeloblasts of AML.

Question 4

Amyloid deposits appear apple-green birefringent under polarized light when stained with?

Accepted Answer

Congo red

Answer

Congo red stain produces the characteristic apple-green birefringence of amyloid.

Question 5

Which of the following is a benign tumor of smooth muscle commonly arising in the uterus?

Accepted Answer

Leiomyoma

Answer

A leiomyoma (fibroid) is a benign smooth-muscle tumor of the myometrium.

American Board of Pathology (ABPath) Practice Test