ABPath Pathology MCQ

Question 1

Which of the following is a common histologic feature of chronic inflammation?

Accepted Answer

Granuloma formation

Answer

Neutrophil infiltration

Answer

Eosinophil infiltration

Answer

Hyperemia

Question 2

What is the most common cause of iron deficiency anemia worldwide?

Accepted Answer

Blood loss

Answer

Malabsorption

Answer

Vitamin B12 deficiency

Answer

Chronic inflammation

Question 3

In which condition would you most likely find hyperkalemia?

Accepted Answer

Chronic kidney disease

Answer

Acute myocardial infarction

Answer

Hyperparathyroidism

Answer

Addison’s disease

Question 4

What is the key difference between malignant and benign tumors?

Accepted Answer

Benign tumors grow slowly, while malignant tumors grow rapidly

Answer

Malignant tumors are encapsulated, while benign tumors are not

Answer

Malignant tumors are always larger than benign tumors

Answer

Benign tumors can invade surrounding tissues, while malignant tumors do not

Question 5

Which of the following is a characteristic feature of retinoblastoma on histopathology?

Accepted Answer

Flexner-Wintersteiner rosettes

Answer

Homer-Wright rosettes

Answer

Pseudoepitheliomatous hyperplasia

Answer

Microcytic hypochromic cells

Question 6

What is the most common cause of myocardial infarction?

Accepted Answer

Atherosclerosis and thrombosis

Answer

Coronary artery spasm

Answer

Hypertension

Answer

Endocarditis

Question 7

Which of the following is the hallmark feature of a fibroid (leiomyoma) on histology?

Accepted Answer

Spindle-shaped smooth muscle cells

Answer

Sheets of malignant cells

Answer

Cystic spaces with blood-filled cavities

Answer

Presence of keratin pearls

Question 8

What is the most common presenting symptom of acute leukemia?

Accepted Answer

Fever and infections

Answer

Abdominal pain

Answer

Severe anemia

Answer

Weight loss

Question 9

What is the primary molecular alteration in the pathogenesis of chronic myelogenous leukemia (CML)?

Accepted Answer

BCR-ABL fusion gene

Answer

TP53 mutation

Answer

EGFR amplification

Answer

MYC oncogene activation