A lymph node biopsy from a 62-year-old male with generalized lymphadenopathy shows a nodular proliferation of crowded follicles composed of centrocytes and centroblasts.
Immunohistochemistry is strongly positive for BCL2 in the germinal centers, as well as CD10 and BCL6.
Flow cytometry confirms a monoclonal B-cell population.
Which of the following cytogenetic abnormalities is most characteristic of this diagnosis?
