ABPath General Pathology Principles 2

Question 1

Which type of necrosis is most characteristically associated with ischemic injury to the myocardium?

Accepted Answer

Coagulative necrosis

Answer

Ischemic injury to solid organs except the brain produces coagulative necrosis, where tissue architecture is preserved.

Question 2

Apoptosis differs from necrosis primarily in that apoptosis:

Accepted Answer

Is energy-dependent and does not incite inflammation

Answer

Apoptosis is an ATP-dependent, programmed cell death that leaves the membrane intact and does not provoke inflammation.

Question 3

Dystrophic calcification is best described as calcium deposition in:

Accepted Answer

Damaged or necrotic tissue with normal serum calcium

Answer

Dystrophic calcification occurs in previously injured or necrotic tissue despite normal serum calcium levels.

Question 4

Which cellular adaptation refers to a decrease in cell size and number leading to reduced organ size?

Accepted Answer

Atrophy

Answer

Atrophy is a reduction in cell size and number, shrinking the tissue or organ.

Question 5

The reversible cellular change of hydropic swelling results primarily from:

Accepted Answer

Failure of the Na+/K+ ATPase pump

Answer

Cellular swelling occurs when the Na+/K+ ATPase fails, causing sodium and water influx into the cell.

American Board of Pathology (ABPath) Practice Test