ABPath Blood Banking and Transfusion 5

Question 1

Transfusion-associated circulatory overload (TACO) is best distinguished from TRALI by which feature?

Accepted Answer

Elevated BNP and response to diuretics

Answer

TACO shows cardiogenic edema with elevated BNP and improves with diuresis, unlike TRALI.

Question 2

Which infectious agent is a major concern for platelet units due to their room-temperature storage?

Accepted Answer

Bacterial contamination

Answer

Room-temperature storage of platelets promotes bacterial growth, the leading infectious risk.

Question 3

An antibody that reacts more strongly with cells expressing a double dose of antigen demonstrates:

Accepted Answer

Dosage effect

Answer

Dosage effect describes stronger reactivity with homozygous (double-dose) antigen expression.

Question 4

Massive transfusion can lead to which metabolic complication from citrate anticoagulant?

Accepted Answer

Hypocalcemia

Answer

Citrate chelates calcium, causing hypocalcemia during massive transfusion.

Question 5

The gel column agglutination method detects antigen-antibody reactions based on:

Accepted Answer

Trapping of agglutinated cells in a dextran gel matrix

Answer

In gel technology, agglutinated cells are trapped in the gel while unagglutinated cells settle to the bottom.

American Board of Pathology (ABPath) Practice Test