ABPath Blood Banking and Transfusion 5

Question 1

Transfusion-associated circulatory overload (TACO) is best distinguished from TRALI by which feature?

Accepted Answer

Elevated BNP and response to diuretics

Answer

Normal blood pressure

Answer

Absence of respiratory symptoms

Answer

Positive DAT

Question 2

Which infectious agent is a major concern for platelet units due to their room-temperature storage?

Accepted Answer

Bacterial contamination

Answer

Hepatitis C virus

Answer

Prions

Answer

Malaria

Question 3

An antibody that reacts more strongly with cells expressing a double dose of antigen demonstrates:

Accepted Answer

Dosage effect

Answer

Prozone

Answer

Rouleaux

Answer

Panagglutination

Question 4

Massive transfusion can lead to which metabolic complication from citrate anticoagulant?

Accepted Answer

Hypocalcemia

Answer

Hyperkalemia only

Answer

Metabolic alkalosis immediately

Answer

Hypernatremia

Question 5

The gel column agglutination method detects antigen-antibody reactions based on:

Accepted Answer

Trapping of agglutinated cells in a dextran gel matrix

Answer

Color change of a substrate

Answer

Precipitation of DNA

Answer

Enzyme-linked fluorescence

Question 6

Which finding best supports a diagnosis of paroxysmal cold hemoglobinuria?

Accepted Answer

A biphasic Donath-Landsteiner antibody with anti-P specificity

Answer

Warm IgG autoantibody

Answer

Anti-I cold agglutinin

Answer

Anti-D alloantibody

Question 7

Before issuing RBCs, the antihuman globulin (AHG) crossmatch primarily ensures:

Accepted Answer

Donor cells are compatible with recipient antibodies

Answer

The donor has no infectious disease

Answer

The recipient is RhD positive

Answer

Platelet function is adequate