ECMO Study Guide 2026

Everything you need to pass the ECMO exam in one place: the exam format, every topic to study, real practice questions with explanations, flashcards, and full-length practice tests. Free, no sign-up needed.

📋 ECMO Exam Format at a Glance

120
Questions
180 min
Time Limit
80%
Passing Score

📚 ECMO Topics to Study (69)

✍️ Sample ECMO Questions & Answers

1. The term 'ECMO-CPR' (ECPR) refers to:
Initiating VA-ECMO during active cardiac arrest to restore perfusion

ECPR is the deployment of VA-ECMO during refractory cardiac arrest to restore systemic perfusion and allow time for resuscitation, intervention, or recovery.

2. Hemolysis in an ECMO circuit is best monitored by measuring:
Plasma-free hemoglobin and lactate dehydrogenase (LDH) levels

Plasma-free hemoglobin and LDH are direct markers of red cell destruction, indicating mechanical trauma from pump cavitation, high negative pressures, or circuit thrombosis.

3. What is the significance of a 'chattering' or 'sucking' cannula during VV ECMO?
It signals that drainage is impaired, usually from hypovolemia or cannula malposition

Cannula chattering occurs when the circuit intermittently collapses venous inflow, indicating inadequate preload or a positional drainage issue requiring immediate attention.

4. What happens to PaCO2 when sweep gas flow is doubled while ECMO blood flow remains constant?
PaCO2 decreases, potentially causing hypocapnia

Doubling sweep gas flow dramatically increases CO2 removal, often causing significant hypocapnia, so sweep adjustments require careful monitoring of blood gas values.

5. The ELSO (Extracorporeal Life Support Organization) registry reports the highest survival rates among which ECMO patient group?
Neonatal respiratory ECMO

Neonatal respiratory ECMO has the best outcomes, with survival to discharge approximately 73% according to ELSO registry data.

6. Following a circuit change for oxygenator failure, the ECMO specialist notes the new circuit's post-membrane pO2 is 500 mmHg on FiO2 1.0. This confirms:
The new oxygenator is functioning appropriately

A post-membrane pO2 of approximately 500 mmHg on 100% FiO2 is the expected result of a fully functional oxygenator, confirming successful circuit exchange.

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Your ECMO Study Path
1. Learn with Flashcards → 2. Drill Practice Tests → 3. Take the Full Exam Simulation
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