In a pedigree analysis, an X-linked recessive trait is suspected. Which observation would MOST strongly support X-linked (rather than autosomal) recessive inheritance?
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A
Affected males are more frequent than affected females and all affected females have affected fathers
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B
The trait skips exactly one generation in every family
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C
Affected individuals appear in equal numbers in both sexes
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D
Two affected parents always produce all affected offspring