AOCNP Advanced Oncology Certified Nurse Practitioner 3

Question 1

Which staging system is used for Hodgkin lymphoma?

Accepted Answer

Ann Arbor staging with Cotswolds modification

Answer

Hodgkin lymphoma is staged using the Ann Arbor system with Cotswolds modification, which includes designators for symptoms and bulky disease.

Question 2

A patient with NSCLC has a PDL-1 expression of 80% and no driver mutations. What is the preferred first-line treatment?

Accepted Answer

Pembrolizumab monotherapy

Answer

Pembrolizumab monotherapy is the preferred first-line treatment for NSCLC with PDL-1 ≥50% and no actionable driver mutations.

Question 3

What is the most common side effect of bevacizumab that requires immediate management?

Accepted Answer

Gastrointestinal perforation

Answer

Gastrointestinal perforation is a serious, potentially life-threatening adverse event associated with bevacizumab requiring immediate intervention.

Question 4

A male patient with metastatic castration-resistant prostate cancer has progressed on enzalutamide. BRCA2 mutation is confirmed. What is the next preferred therapy?

Accepted Answer

Olaparib

Answer

Olaparib, a PARP inhibitor, is approved for BRCA-mutated metastatic castration-resistant prostate cancer after progression on enzalutamide or abiraterone.

Question 5

Which paraneoplastic syndrome is most commonly associated with small cell lung cancer?

Accepted Answer

Syndrome of inappropriate antidiuretic hormone (SIADH)

Answer

SIADH, caused by ectopic ADH production, is the most common paraneoplastic syndrome associated with small cell lung cancer.

AOCNP - Advanced Oncology Certified Nurse Practitioner Practice Test

AOCNP - Advanced Oncology Certified Nurse Practitioner Practice Test

AOCNP Advanced Oncology Certified Nurse Practitioner 3