AOCNP Oncologic Emergencies 3

Question 1

The MASCC score is used to stratify risk in which oncologic condition?

Accepted Answer

Febrile neutropenia

Answer

The Multinational Association for Supportive Care in Cancer (MASCC) score identifies low-risk febrile neutropenia patients who may be managed with oral antibiotics outpatient.

Question 2

What is the preferred initial antibiotic for low-risk febrile neutropenia being managed outpatient?

Accepted Answer

Ciprofloxacin plus amoxicillin-clavulanate

Answer

Oral ciprofloxacin combined with amoxicillin-clavulanate is the IDSA-recommended outpatient regimen for low-risk febrile neutropenia.

Question 3

Syndrome of inappropriate antidiuretic hormone secretion (SIADH) in cancer is best managed initially with:

Accepted Answer

Fluid restriction to 800–1000 mL/day

Answer

Mild to moderate SIADH is first managed with fluid restriction; hypertonic saline is reserved for severe symptomatic hyponatremia.

Question 4

A patient with AML develops bleeding gums, petechiae, prolonged PT/PTT, low fibrinogen, and elevated D-dimer. Which treatment is specific to this etiology?

Accepted Answer

All-trans retinoic acid (ATRA)

Answer

ATRA induces differentiation of promyelocytes in APL-associated DIC, addressing the underlying cause rather than just replacing clotting factors.

Question 5

Which imaging finding on MRI spine best confirms malignant spinal cord compression requiring urgent treatment?

Accepted Answer

Epidural tumor impinging on the thecal sac

Answer

Epidural tumor directly impinging on the thecal sac confirms cord compression and necessitates urgent corticosteroids and radiation or surgery.

AOCNP - Advanced Oncology Certified Nurse Practitioner Practice Test

AOCNP - Advanced Oncology Certified Nurse Practitioner Practice Test

AOCNP Oncologic Emergencies 3