AOCNP Oncologic Emergencies 3

Question 1

The MASCC score is used to stratify risk in which oncologic condition?

Accepted Answer

Febrile neutropenia

Answer

Tumor lysis syndrome

Answer

Hypercalcemia of malignancy

Answer

Spinal cord compression

Question 2

What is the preferred initial antibiotic for low-risk febrile neutropenia being managed outpatient?

Accepted Answer

Ciprofloxacin plus amoxicillin-clavulanate

Answer

IV vancomycin

Answer

Oral metronidazole

Answer

IV meropenem

Question 3

Syndrome of inappropriate antidiuretic hormone secretion (SIADH) in cancer is best managed initially with:

Accepted Answer

Fluid restriction to 800–1000 mL/day

Answer

IV 3% hypertonic saline immediately

Answer

Diuresis with furosemide alone

Answer

Oral sodium supplementation

Question 4

A patient with AML develops bleeding gums, petechiae, prolonged PT/PTT, low fibrinogen, and elevated D-dimer. Which treatment is specific to this etiology?

Accepted Answer

All-trans retinoic acid (ATRA)

Answer

Fresh frozen plasma alone

Answer

Platelet transfusion alone

Answer

Heparin infusion

Question 5

Which imaging finding on MRI spine best confirms malignant spinal cord compression requiring urgent treatment?

Accepted Answer

Epidural tumor impinging on the thecal sac

Answer

Vertebral body sclerosis without cord contact

Answer

Disc degeneration with osteophytes

Answer

Paraspinal muscle edema only

Question 6

Which intervention is contraindicated in the initial management of SVC syndrome with thrombosis?

Accepted Answer

Immediate surgical resection as first-line therapy

Answer

Anticoagulation

Answer

Glucocorticoids for symptom relief

Answer

Catheter-directed thrombolysis