VTNE Veterinary Pharmacology 4

Question 1

A patient is receiving aminoglycoside antibiotics. Which parameter is most important to monitor for toxicity?

Accepted Answer

Renal function (BUN, creatinine)

Answer

Aminoglycosides (e.g., gentamicin, amikacin) are nephrotoxic and ototoxic; renal function parameters should be monitored closely during treatment.

Question 2

Which drug is the antidote for acetaminophen toxicity in cats?

Accepted Answer

N-acetylcysteine

Answer

N-acetylcysteine replenishes glutathione stores and is the antidote for acetaminophen toxicity, which causes methemoglobinemia and hepatotoxicity in cats.

Question 3

What is the mechanism by which metronidazole kills anaerobic bacteria?

Accepted Answer

Forms toxic free radicals that damage DNA after reduction in anaerobic conditions

Answer

Metronidazole is reduced by anaerobic organisms into reactive intermediates that form free radicals, causing lethal DNA strand breakage.

Question 4

Propofol is classified as which type of anesthetic agent?

Accepted Answer

Injectable short-acting hypnotic

Answer

Propofol is a phenol-based injectable hypnotic/anesthetic with rapid onset and short duration, used for induction and total intravenous anesthesia (TIVA).

Question 5

Which of the following correctly describes the pharmacokinetic term 'half-life'?

Accepted Answer

The time required for the plasma concentration of a drug to decrease by 50%

Answer

Half-life (t½) is the time required for the drug's plasma concentration to decrease by 50%, determining dosing intervals and time to steady state.

VTNE - Veterinary Technician National Examination Practice Test

VTNE - Veterinary Technician National Examination Practice Test

VTNE Veterinary Pharmacology 4