VTNE Pharmacy and Pharmacology 3

Question 1

Which adverse effect is most associated with chronic NSAID use in dogs?

Accepted Answer

Gastrointestinal ulceration

Answer

Chronic NSAID use inhibits COX-1, reducing protective prostaglandins in the GI tract and predisposing patients to ulcers.

Question 2

A veterinarian prescribes enalapril for a dog with congestive heart failure. What drug class does enalapril belong to?

Accepted Answer

ACE inhibitor

Answer

Enalapril is an ACE (angiotensin-converting enzyme) inhibitor used to reduce cardiac workload in heart failure.

Question 3

Which drug is used as the antidote for acetaminophen toxicity in cats?

Accepted Answer

N-acetylcysteine

Answer

N-acetylcysteine replenishes glutathione stores, helping to neutralize the toxic metabolite NAPQI formed from acetaminophen.

Question 4

What is the term for the time it takes for a drug's plasma concentration to decrease by 50%?

Accepted Answer

Half-life

Answer

Half-life (t½) is the time required for the plasma concentration of a drug to fall to half its original value.

Question 5

Which drug is commonly used as a preanesthetic to reduce salivation and bradycardia in veterinary patients?

Accepted Answer

Atropine

Answer

Atropine is an anticholinergic drug that blocks muscarinic receptors, reducing secretions and preventing vagally-induced bradycardia.

VTNE - Veterinary Technician National Examination Practice Test