PTCB Sterile Compounding & Pharmacy Calculations

Question 1

What type of environment is required for preparing sterile IV admixtures?

Accepted Answer

Laminar airflow workbench (LAFW) or ISO 5 environment

Answer

Sterile IV preparations must be prepared in an ISO 5 (Class 100) environment using a laminar airflow workbench to minimize contamination.

Question 2

How many milligrams are in 2 grams?

Accepted Answer

2000 mg

Answer

There are 1,000 milligrams in 1 gram, so 2 grams = 2,000 mg.

Question 3

A vial contains 500 mg/10 mL. How many mL are needed to prepare a 250 mg dose?

Accepted Answer

5 mL

Answer

500 mg/10 mL = 50 mg/mL; 250 mg ÷ 50 mg/mL = 5 mL needed.

Question 4

What is the beyond-use date (BUD) for a low-risk sterile preparation stored at room temperature according to USP <797>?

Accepted Answer

24 hours

Answer

USP <797> assigns low-risk sterile preparations a maximum BUD of 48 hours at controlled room temperature.

Question 5

Which type of hood is used for preparing hazardous sterile preparations (e.g., chemotherapy)?

Accepted Answer

Biological safety cabinet (BSC) Class II

Answer

Hazardous sterile preparations require a Class II Biological Safety Cabinet (BSC) with vertical laminar flow and exhaust HEPA filtration to protect the preparer.

PTCB - Pharmacy Technician Certification Board Practice Test

PTCB - Pharmacy Technician Certification Board Practice Test

PTCB Sterile Compounding & Pharmacy Calculations