PTCB Pharmacology for Technicians

Question 1

What is the mechanism of action of NSAIDs?

Accepted Answer

Inhibit COX enzymes to reduce prostaglandin synthesis

Answer

NSAIDs work by inhibiting cyclooxygenase (COX-1 and COX-2) enzymes, reducing the production of prostaglandins that cause pain and inflammation.

Question 2

Which drug is the antidote for acetaminophen overdose?

Accepted Answer

N-acetylcysteine

Answer

N-acetylcysteine (Mucomyst, Acetadote) is the antidote for acetaminophen toxicity, replenishing glutathione stores to prevent liver damage.

Question 3

What is the antidote for opioid overdose?

Accepted Answer

Naloxone

Answer

Naloxone (Narcan) is an opioid receptor antagonist that rapidly reverses opioid-induced respiratory depression.

Question 4

Which electrolyte imbalance is a common side effect of loop diuretics like furosemide?

Accepted Answer

Hypokalemia

Answer

Loop diuretics cause increased urinary excretion of potassium, leading to hypokalemia (low blood potassium levels).

Question 5

What is the main therapeutic use of digoxin?

Accepted Answer

Heart failure and atrial fibrillation

Answer

Digoxin is a cardiac glycoside used to improve myocardial contractility in heart failure and control ventricular rate in atrial fibrillation.

PTCB - Pharmacy Technician Certification Board Practice Test