PTCB Pharmacology for Technicians 2

Question 1

Which drug interaction occurs between warfarin and vitamin K?

Accepted Answer

Antagonistic — vitamin K reduces warfarin's effectiveness

Answer

Vitamin K antagonizes warfarin by providing the substrate warfarin works to deplete, reducing anticoagulant effect and lowering INR.

Question 2

What is the term for the time it takes for a drug's plasma concentration to decrease by 50%?

Accepted Answer

Half-life

Answer

The half-life (t½) is the time required for the drug concentration in the plasma to decrease by half, determining dosing intervals.

Question 3

Which of the following is a potential side effect of long-term corticosteroid use?

Accepted Answer

Osteoporosis

Answer

Long-term corticosteroid use can cause osteoporosis by inhibiting osteoblast activity and increasing calcium excretion.

Question 4

Insulin glargine is classified as which type of insulin?

Accepted Answer

Long-acting (basal)

Answer

Insulin glargine (Lantus, Basaglar) is a long-acting basal insulin with a duration of approximately 24 hours.

Question 5

Which drug class can cause photosensitivity as a side effect?

Accepted Answer

Tetracycline antibiotics

Answer

Tetracycline antibiotics (e.g., doxycycline) frequently cause photosensitivity, increasing the risk of sunburn.

PTCB - Pharmacy Technician Certification Board Practice Test