Physician Assistant Cardiovascular System Disorders 4 — Questions and Answers
Question 1: Which finding is MOST characteristic of constrictive pericarditis on physical exam?
- Loud S1 heart sound
- Kussmaul's sign (JVD increasing with inspiration) (Correct answer)
- Pulsus alternans
- Friction rub that disappears with leaning forward
Correct answer: Kussmaul's sign (JVD increasing with inspiration)
Kussmaul's sign — paradoxical rise in JVP during inspiration — is a classic finding in constrictive pericarditis.
Question 2: A 30-year-old athlete collapses during a basketball game. ECG shows asymmetric septal hypertrophy. What is the most likely diagnosis?
- Dilated cardiomyopathy
- Hypertrophic obstructive cardiomyopathy (Correct answer)
- Arrhythmogenic right ventricular cardiomyopathy
- Myocarditis
Correct answer: Hypertrophic obstructive cardiomyopathy
HOCM is the most common cause of sudden cardiac death in young athletes and presents with asymmetric septal hypertrophy.
Question 3: Which statement about the management of STEMI is correct?
- Fibrinolysis is preferred over PCI when door-to-balloon time is under 90 minutes
- Primary PCI is preferred when door-to-balloon time is under 120 minutes (Correct answer)
- Anticoagulation is not required if PCI is performed
- Aspirin should be withheld until after revascularization
Correct answer: Primary PCI is preferred when door-to-balloon time is under 120 minutes
Primary PCI is the preferred reperfusion strategy for STEMI when it can be performed within 90-120 minutes of first medical contact.
Question 4: A patient's ECG shows a prolonged PR interval, but all P waves are conducted. What rhythm is this?
- Second-degree AV block Mobitz I
- Second-degree AV block Mobitz II
- First-degree AV block (Correct answer)
- Third-degree AV block
Correct answer: First-degree AV block
First-degree AV block is defined by a PR interval >200 ms with all P waves conducted to the ventricles.
Question 5: A patient with peripheral artery disease has an ABI of 0.55. What does this indicate?
- Normal arterial perfusion
- Mild PAD
- Moderate-to-severe PAD (Correct answer)
- Non-compressible vessels (calcification)
Correct answer: Moderate-to-severe PAD
An ABI of 0.41–0.70 indicates moderate-to-severe peripheral arterial disease with significant hemodynamic compromise.
Question 6: Which medication class is first-line for long-term rate control in atrial fibrillation in a patient with heart failure with reduced ejection fraction?
- Non-dihydropyridine calcium channel blockers
- Digoxin alone
- Beta-blockers (Correct answer)
- Class IC antiarrhythmics
Correct answer: Beta-blockers
Beta-blockers (e.g., carvedilol, metoprolol succinate) are first-line for rate control in AF with HFrEF and provide mortality benefit.
Question 7: A 50-year-old woman presents with dyspnea and a loud S2 with fixed splitting. What is the most likely diagnosis?
- Ventricular septal defect
- Atrial septal defect (Correct answer)
- Patent ductus arteriosus
- Pulmonary stenosis
Correct answer: Atrial septal defect
Fixed wide splitting of S2 that does not vary with respiration is pathognomonic for an atrial septal defect.
Which finding is MOST characteristic of constrictive pericarditis on physical exam?