FREE Physician Assistant Pharmaceutical Therapeutics Questions and Answers

Question 1

A 58-year-old male with type 2 diabetes, hypertension, and a history of myocardial infarction has an A1c of 8.1% despite being on metformin.
Which of the following medication classes, when added to his regimen, has been shown to reduce cardiovascular mortality in patients with established atherosclerotic cardiovascular disease?

Accepted Answer

Sodium-glucose cotransporter-2 (SGLT-2) inhibitors

Answer

Dipeptidyl peptidase-4 (DPP-4) inhibitors

Answer

Sulfonylureas

Answer

Thiazolidinediones (TZDs)

Question 2

A 35-year-old patient describes a history of debilitating, unilateral, throbbing headaches occurring 2-3 times per month, accompanied by photophobia and nausea. Which of the following is the most appropriate first-line abortive medication for moderate to severe acute attacks?

Accepted Answer

Sumatriptan

Answer

Propranolol

Answer

Amitriptyline

Answer

Verapamil

Question 3

A 45-year-old, otherwise healthy male with no comorbidities or recent antibiotic use is diagnosed with community-acquired pneumonia (CAP) in an outpatient setting. According to the most recent IDSA/ATS guidelines, which of the following is a recommended first-line empiric monotherapy?

Accepted Answer

Amoxicillin

Answer

Levofloxacin

Answer

Vancomycin

Answer

Ceftriaxone

Question 4

A 55-year-old is newly diagnosed with moderate-to-severe, active rheumatoid arthritis. Which of the following disease-modifying antirheumatic drugs (DMARDs) is most commonly recommended as initial monotherapy?

Accepted Answer

Methotrexate

Answer

Adalimumab

Answer

Hydroxychloroquine

Answer

Prednisone

Question 5

A 29-year-old is diagnosed with Major Depressive Disorder (MDD) of moderate severity and has no other medical conditions. Which of the following is considered a first-line pharmacologic treatment for this patient?

Accepted Answer

Sertraline

Answer

Lithium

Answer

Alprazolam

Answer

Amitriptyline

Question 6

A patient with frequent symptoms of gastroesophageal reflux disease (GERD) and evidence of erosive esophagitis on endoscopy has failed to respond to lifestyle changes. Which medication class is the most effective for providing symptom relief and promoting healing of the esophagus?

Accepted Answer

Proton Pump Inhibitors (PPIs)

Answer

H2-receptor antagonists

Answer

Antacids

Answer

Prokinetic agents