Pharm.D. Doctor of Pharmacy Clinical Pharmacy and Patient Care 1

Question 1

Which parameter is used to assess kidney function most commonly in clinical practice for drug dosing?

Accepted Answer

Creatinine clearance (CrCl) estimated by Cockcroft-Gault

Answer

The Cockcroft-Gault equation is the most widely used method to estimate creatinine clearance for drug dosing adjustment in clinical practice.

Question 2

A patient on warfarin is started on ciprofloxacin. What interaction should the clinical pharmacist anticipate?

Accepted Answer

Increased INR due to reduced warfarin metabolism and gut flora suppression

Answer

Ciprofloxacin inhibits CYP1A2 and suppresses gut flora that produce vitamin K, leading to increased warfarin effect and elevated INR.

Question 3

Which medication reconciliation step is MOST critical at hospital discharge?

Accepted Answer

Comparing discharge medications to pre-admission medications and counseling the patient

Answer

At discharge, comparing the new medication list to pre-admission medications and counseling the patient prevents inadvertent duplication, omission, or errors.

Question 4

Which clinical pharmacy service is MOST associated with reducing hospital readmissions for heart failure patients?

Accepted Answer

Medication therapy management (MTM) and adherence counseling

Answer

MTM with adherence counseling helps heart failure patients understand their complex regimens, improving adherence and reducing readmissions.

Question 5

A patient presents with signs of digoxin toxicity. Which electrolyte abnormality most potentiates this toxicity?

Accepted Answer

Hypokalemia

Answer

Hypokalemia potentiates digoxin toxicity because low potassium increases digoxin binding to Na+/K+-ATPase, enhancing its toxic effects.

Pharm.D. Doctor of Pharmacy Practice Test

Pharm.D. Doctor of Pharmacy Practice Test

Pharm.D. Doctor of Pharmacy Clinical Pharmacy and Patient Care 1