Free Doctor of Pharmacy Questions and Answers

Question 1

Which of the following best describes how acetaminophen is metabolized?

Accepted Answer

Glucuronidation

Answer

Sulfation

Answer

Cytochrome P-450 oxidation

Answer

Plasma breakdown

Question 2

A 15-year-old appears with nasal congestion and thin, clear rhinorrhea that has lasted for six days. She reports some minor facial soreness but no fevers. She thinks her symptoms are getting better. Which factor accounts for her symptoms most likely?

Accepted Answer

Viral

Answer

Staphylococcus aureus

Answer

Streptococcus pneumoniae

Answer

Moraxella catarrhalis

Question 3

A woman in her 72s is going through a severe depression episode. Her medical history includes glaucoma, chronic obstructive pulmonary disease, sick sinus syndrome, atrial fibrillation while taking anticoagulant therapy, and coronary artery disease. Which drug from the list below is ideal for treating her depression?

Accepted Answer

Escitalopram

Answer

Doxepin

Answer

Amitriptyline

Answer

Nortriptyline

Question 4

What anti-thyroid treatment is most effective for pregnant women with clinically severe hyperthyroidism?

Accepted Answer

Propylthiouracil first trimester followed by methimazole for the remainder of pregnancy

Answer

Methimazole first trimester followed by propylthiouracil for the remainder of pregnancy

Answer

Stop treatment and resume post-partum

Answer

Propylthiouracil

Question 5

Which of the following statements about medication absorption is accurate?

Accepted Answer

After oral ingestion of drugs, the absorption of drug may be incomplete

Answer

Grape juice activates P-glycoprotein leading to substantial inhibition of absorption of drugs

Answer

Drugs which are too lipophilic cannot cross the lipid cell membrane

Answer

P-glycoprotein is an efflux transporter which is present in the enterocytes and it enhances the absorption of drug

Question 6

Your patient, a 58-year-old man, complains of sudden, intense shortness of breath and substernal chest pain. He is en route to the cardiac catheterization suite for percutaneous coronary intervention after an ECG reveals an acute STEMI. Which of the following medications used to treat acute coronary syndromes with PCI requires oxidation to an active form by hepatic P450 enzymes?

Accepted Answer

Clopidogrel

Answer

Warfarin

Answer

Eptifibatide

Answer

Ticlopidine

Question 7

Dapsone, clofazimine, and rifampin are being taken by a patient with multibacillary leprosy. Which of the following statements about the drugs on this list actually describes how they work?

Accepted Answer

Rifampin is bactericidal by inhibiting RNA synthesis by blocking DNA-dependent RNA polymerase

Answer

Rifampin is bacteriostatic by inhibiting RNA synthesis by blocking DNA-dependent RNA polymerase

Answer

Dapsone is bacteriostatic because of its inhibitory effects on myeloperoxidase

Answer

Clofazimine is bactericidal by directly inhibiting bacterial DNA polymerase