NAVLE Veterinary Pharmacology 4

Question 1

A dog receives an overdose of acepromazine. Which statement about acepromazine reversal is correct?

Accepted Answer

There is no specific reversal agent; treatment is supportive

Answer

Acepromazine, a phenothiazine tranquilizer, has no specific reversal agent; management consists of supportive care including IV fluids and vasopressors for hypotension.

Question 2

Which class of drugs can cause crystalluria and urinary obstruction in dogs, particularly in acidic urine?

Accepted Answer

Sulfonamides

Answer

Sulfonamides can precipitate in acidic urine and form crystals, potentially causing crystalluria, hematuria, and renal tubular obstruction.

Question 3

A cattle producer wants to treat a cow with bacterial pneumonia. Which beta-lactam antibiotic has an approved long-acting formulation for cattle?

Accepted Answer

Ceftiofur

Answer

Ceftiofur (as ceftiofur crystalline free acid) has a long-acting formulation approved in cattle that provides therapeutic concentrations for several days.

Question 4

What is the primary concern when using ketamine as the sole anesthetic in a dog?

Accepted Answer

Inadequate muscle relaxation and increased muscle tone

Answer

Ketamine alone causes increased muscle tone and catalepsy rather than muscle relaxation, so it is typically combined with a benzodiazepine or alpha-2 agonist for adequate relaxation.

Question 5

Which drug used in cattle to synchronize estrus can cause luteolysis by acting on the corpus luteum?

Accepted Answer

Prostaglandin F2α (PGF2α)

Answer

Prostaglandin F2α causes regression of the corpus luteum (luteolysis), leading to a decrease in progesterone and allowing the next follicular wave to result in estrus.

NAVLE - North American Veterinary Licensing Examination Practice Test

NAVLE - North American Veterinary Licensing Examination Practice Test

NAVLE Veterinary Pharmacology 4