NAVLE Feline Infectious 2

Question 1

A cat presents with corneal sequestrum and chronic ocular discharge. Which herpesvirus is most commonly implicated in this condition?

Accepted Answer

Feline herpesvirus-1

Answer

Feline herpesvirus-1 (FHV-1) is strongly associated with corneal sequestrum formation due to chronic corneal inflammation and ulceration.

Question 2

Which feline coronavirus (FCoV) mutation is classically associated with the transition from enteric infection to feline infectious peritonitis (FIP)?

Accepted Answer

3c gene loss-of-function mutation

Answer

Loss-of-function mutations in the 3c gene of feline enteric coronavirus are associated with the shift to macrophage tropism and development of FIP.

Question 3

A 3-year-old intact male cat tests FIV-positive. What is the most reliable route of transmission for this virus?

Accepted Answer

Bite wounds

Answer

FIV is most efficiently transmitted through bite wounds because high viral loads are present in saliva.

Question 4

Feline panleukopenia virus (FPV) primarily targets which tissue due to its requirement for rapidly dividing cells?

Accepted Answer

Intestinal crypt epithelium

Answer

FPV targets rapidly dividing intestinal crypt cells, leading to villous collapse, malabsorption, and severe hemorrhagic enteritis.

Question 5

A cat with confirmed FeLV infection is most likely to develop which neoplastic condition?

Accepted Answer

Multicentric lymphoma

Answer

FeLV strongly predisposes cats to multicentric lymphoma, particularly T-cell lymphoma in young cats.

NAVLE - North American Veterinary Licensing Examination Practice Test