CN Pharmacology & Drug Administration 2

Question 1

Which term describes what the body does to a drug, including absorption, distribution, metabolism, and excretion?

Accepted Answer

Pharmacokinetics

Answer

Pharmacokinetics is the study of drug movement through the body (ADME).

Question 2

A client takes warfarin and consumes large amounts of vitamin K-rich greens. What is the likely effect?

Accepted Answer

Decreased anticoagulation

Answer

Vitamin K antagonizes warfarin, reducing its anticoagulant effect.

Question 3

Grapefruit juice can raise blood levels of certain drugs primarily by inhibiting which enzyme?

Accepted Answer

CYP3A4

Answer

Grapefruit inhibits intestinal CYP3A4, increasing systemic drug concentrations.

Question 4

Which route of administration generally provides the fastest onset of systemic effect?

Accepted Answer

Intravenous

Answer

IV delivers the drug directly into the bloodstream, bypassing absorption.

Question 5

A statin depletes the body's synthesis of which nutrient-like compound?

Accepted Answer

Coenzyme Q10

Answer

Statins reduce CoQ10 synthesis via the same mevalonate pathway they block.

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