AOCNP Survivorship and Long-Term Follow-Up 5

Question 1

A male survivor of testicular cancer treated with bleomycin reports progressive dyspnea and a dry cough. Pulmonary function testing reveals reduced DLCO. The most likely etiology is:

Accepted Answer

Bleomycin-induced pulmonary toxicity

Answer

Bleomycin is well-known for causing pulmonary fibrosis, characterized by reduced DLCO and restrictive ventilatory defects as a late toxicity.

Question 2

A survivor of colorectal cancer asks about surveillance colonoscopy timing. According to ASCO guidelines, when should the first post-treatment colonoscopy be performed after curative resection?

Accepted Answer

1 year post-surgery

Answer

ASCO recommends a colonoscopy 1 year after curative resection of colorectal cancer to detect metachronous lesions.

Question 3

A breast cancer survivor on long-term tamoxifen therapy is at increased risk for which gynecologic late effect requiring surveillance?

Accepted Answer

Endometrial cancer

Answer

Tamoxifen's partial estrogen agonist activity on the uterine endometrium increases the risk of endometrial cancer, requiring vigilance for abnormal uterine bleeding.

Question 4

In a survivor who received cisplatin-based chemotherapy, which audiologic late effect should the AOCNP specifically monitor for during follow-up?

Accepted Answer

High-frequency sensorineural hearing loss

Answer

Cisplatin-induced ototoxicity typically manifests as high-frequency sensorineural hearing loss that can be permanent and progressive.

Question 5

A 10-year survivor of breast cancer presents with arm swelling, heaviness, and pitting edema after a recent air travel. The MOST likely diagnosis is:

Accepted Answer

Lymphedema

Answer

Lymphedema is a common late effect following axillary lymph node dissection and/or radiation, and can be triggered or worsened by air travel.

AOCNP - Advanced Oncology Certified Nurse Practitioner Practice Test

AOCNP - Advanced Oncology Certified Nurse Practitioner Practice Test

AOCNP Survivorship and Long-Term Follow-Up 5