AOCNP Cancer Screening and Prevention 5

Question 1

A 70-year-old woman asks about cervical cancer screening. Which recommendation is most appropriate for an average-risk woman her age?

Accepted Answer

Discontinue screening if she has had adequate prior screening with no abnormal results

Answer

Women aged 65 and older with adequate prior negative screening can discontinue cervical cancer screening per USPSTF guidelines.

Question 2

Which modifiable risk factor has the strongest evidence for reducing colorectal cancer incidence?

Accepted Answer

Regular physical activity and maintaining healthy weight

Answer

Regular physical activity and maintaining a healthy body weight have the strongest evidence for reducing colorectal cancer risk among modifiable lifestyle factors.

Question 3

A patient with Li-Fraumeni syndrome (TP53 germline mutation) should avoid which imaging modality for surveillance when possible?

Accepted Answer

Ionizing radiation (CT and X-ray)

Answer

Patients with Li-Fraumeni syndrome have impaired DNA repair and are especially susceptible to radiation-induced cancers, so ionizing radiation should be minimized.

Question 4

Aspirin is being studied as a chemopreventive agent for colorectal cancer. Which patient characteristic most strongly supports its use in this context?

Accepted Answer

Lynch syndrome with prior colorectal polyps

Answer

Patients with Lynch syndrome have shown significant colorectal cancer risk reduction with aspirin use in clinical trials such as CAPP2.

Question 5

Which screening tool is recommended by the American Cancer Society for early detection of prostate cancer in high-risk men (African American or first-degree relative with prostate cancer before age 65)?

Accepted Answer

PSA discussion and shared decision-making starting at age 40

Answer

High-risk men should have a shared decision-making conversation about PSA-based prostate cancer screening starting at age 40.

AOCNP - Advanced Oncology Certified Nurse Practitioner Practice Test

AOCNP - Advanced Oncology Certified Nurse Practitioner Practice Test

AOCNP Cancer Screening and Prevention 5