AOCNP Cancer Screening and Early Detection 5

Question 1

A 58-year-old woman with dense breasts on mammography has a negative mammogram. Which supplemental screening modality has the strongest evidence for increasing cancer detection in this population?

Accepted Answer

Annual ultrasound added to mammography

Answer

Supplemental ultrasound increases cancer detection by approximately 4 per 1,000 women with dense breasts, though it also increases false-positive rates; MRI is reserved for higher-risk women.

Question 2

Which stool-based colorectal cancer screening test requires the MOST frequent testing interval?

Accepted Answer

Guaiac fecal occult blood test (gFOBT)

Answer

The guaiac FOBT (e.g., Hemoccult) requires annual testing, the same as FIT, while Cologuard is recommended every 1-3 years; all have the same annual or more frequent interval for gFOBT.

Question 3

An AOCNP is reviewing risk stratification for hepatocellular carcinoma (HCC) screening. Which patient population has a clear evidence-based indication for surveillance?

Accepted Answer

Patients with cirrhosis from any cause and hepatitis B carriers with high viral load or family history

Answer

HCC surveillance with ultrasound ± AFP every 6 months is recommended for patients with cirrhosis of any etiology and for hepatitis B carriers meeting AASLD high-risk criteria.

Question 4

A nurse practitioner counsels a 42-year-old with a strong family history of melanoma. Which statement about melanoma screening is accurate?

Accepted Answer

USPSTF states there is insufficient evidence to recommend skin cancer screening for adults in primary care

Answer

The USPSTF issued an 'I' statement (insufficient evidence) for skin cancer screening by clinicians in asymptomatic adults, though high-risk patients are often referred to dermatology.

Question 5

Which cervical cancer screening strategy is preferred for a 35-year-old woman per current ASCCP/ACS guidelines?

Accepted Answer

HPV primary testing alone every 5 years

Answer

Current ACS guidelines prefer HPV primary testing every 5 years for ages 25-65; co-testing every 5 years is an acceptable alternative when primary HPV testing is unavailable.

AOCNP - Advanced Oncology Certified Nurse Practitioner Practice Test

AOCNP - Advanced Oncology Certified Nurse Practitioner Practice Test

AOCNP Cancer Screening and Early Detection 5