Which pathophysiologic feature best characterizes type 2 diabetes mellitus?
-
A
Autoimmune destruction of pancreatic beta cells causing absolute insulin deficiency
-
B
Insulin resistance in skeletal muscle, liver, and adipose tissue with progressively inadequate beta-cell insulin secretion
-
C
Excess glucagon secretion from a pancreatic tumor
-
D
Impaired renal glucose reabsorption with normal insulin action