ABO Uveitis 2

Question 1

Which presentation is most characteristic of HLA-B27-associated anterior uveitis?

Accepted Answer

Acute unilateral, recurrent, often alternating nongranulomatous iritis with fibrin

Answer

HLA-B27 uveitis classically presents as sudden unilateral, alternating, recurrent anterior uveitis, often with fibrin or hypopyon.

Question 2

Large greasy 'mutton-fat' keratic precipitates with Busacca nodules most strongly suggest which etiology?

Accepted Answer

Sarcoidosis

Answer

Mutton-fat KPs and iris nodules indicate granulomatous inflammation, classically sarcoidosis.

Question 3

A 35-year-old has unilateral chronic low-grade iritis, diffuse stellate keratic precipitates, iris heterochromia, and no posterior synechiae. Which virus is most associated with this condition?

Accepted Answer

Rubella virus

Answer

Fuchs uveitis syndrome is strongly linked to intraocular rubella virus, with CMV implicated in some cases.

Question 4

A patient has recurrent unilateral episodes of markedly elevated IOP (50 mmHg) with mild anterior chamber reaction and few fine keratic precipitates. Aqueous PCR is most likely to show which pathogen?

Accepted Answer

Cytomegalovirus

Answer

Posner-Schlossman (glaucomatocyclitic crisis) is frequently associated with CMV in immunocompetent patients.

Question 5

Which child with juvenile idiopathic arthritis has the highest risk of developing uveitis?

Accepted Answer

4-year-old ANA-positive girl with oligoarticular JIA diagnosed 1 year ago

Answer

Young age at onset, oligoarticular disease, ANA positivity, and short disease duration carry the highest risk of asymptomatic chronic anterior uveitis.

ABO - American Board of Ophthalmology Practice Test

ABO - American Board of Ophthalmology Practice Test

ABO Uveitis 2