OCN Cancer Treatment Modalities 2

Question 1

Which of the following is a cell-cycle-specific chemotherapy agent?

Accepted Answer

Vincristine

Answer

Vincristine is cell-cycle-specific, acting in the M phase by binding to tubulin and preventing spindle formation.

Question 2

What cumulative dose of doxorubicin is associated with the greatest risk of cardiomyopathy?

Accepted Answer

450–550 mg/m²

Answer

Cardiotoxicity from doxorubicin significantly increases when the cumulative dose exceeds 450–550 mg/m².

Question 3

A patient receiving irinotecan develops profuse diarrhea within 24 hours of infusion. This is best managed with:

Accepted Answer

Atropine

Answer

Early-onset diarrhea with irinotecan is cholinergic in nature and is treated with atropine.

Question 4

Which type of radiation therapy delivers a high dose to a small target with steep dose fall-off, minimizing exposure to surrounding tissue?

Accepted Answer

Stereotactic radiosurgery (SRS)

Answer

Stereotactic radiosurgery (SRS) delivers high-dose, precise radiation to a small target using multiple beams that converge, sparing surrounding tissue.

Question 5

Which of the following is a common dose-limiting toxicity of cisplatin?

Accepted Answer

Nephrotoxicity

Answer

Cisplatin causes significant nephrotoxicity; aggressive hydration and amifostine may be used to minimize renal damage.

OCN Exam Practice Test

OCN Exam Practice Test

OCN Cancer Treatment Modalities 2