OCN Cancer Treatment Modalities

Question 1

Which chemotherapy agent is classified as an alkylating agent?

Accepted Answer

Cyclophosphamide

Answer

Vincristine

Answer

Doxorubicin

Answer

Methotrexate

Question 2

What is the primary mechanism of action of taxanes such as paclitaxel?

Accepted Answer

Stabilizing microtubules to prevent mitosis

Answer

DNA cross-linking

Answer

Inhibiting topoisomerase II

Answer

Blocking folate metabolism

Question 3

A patient receiving external beam radiation develops brisk erythema and moist desquamation. This is classified as what grade of acute skin toxicity per CTCAE?

Accepted Answer

Grade 3

Answer

Grade 1

Answer

Grade 2

Answer

Grade 4

Question 4

Which route of administration is used for intrathecal chemotherapy?

Accepted Answer

Into the cerebrospinal fluid space

Answer

Intravenous

Answer

Subcutaneous

Answer

Intraperitoneal

Question 5

What is the nadir in the context of chemotherapy administration?

Accepted Answer

The point of lowest blood cell counts after chemotherapy

Answer

The peak drug concentration in blood

Answer

The cumulative lifetime dose limit

Answer

The first day of a new chemotherapy cycle

Question 6

A patient is prescribed bevacizumab. The nurse knows this drug targets which molecular pathway?

Accepted Answer

Vascular endothelial growth factor (VEGF)

Answer

HER2/neu receptor

Answer

BCR-ABL tyrosine kinase

Answer

EGFR tyrosine kinase