OCN Cancer Treatment Modalities 2

Question 1

Which of the following is a cell-cycle-specific chemotherapy agent?

Accepted Answer

Vincristine

Answer

Cyclophosphamide

Answer

Carmustine

Answer

Cisplatin

Question 2

What cumulative dose of doxorubicin is associated with the greatest risk of cardiomyopathy?

Accepted Answer

450–550 mg/m²

Answer

100 mg/m²

Answer

200 mg/m²

Answer

750 mg/m²

Question 3

A patient receiving irinotecan develops profuse diarrhea within 24 hours of infusion. This is best managed with:

Accepted Answer

Atropine

Answer

Loperamide

Answer

Octreotide

Answer

Metoclopramide

Question 4

Which type of radiation therapy delivers a high dose to a small target with steep dose fall-off, minimizing exposure to surrounding tissue?

Accepted Answer

Stereotactic radiosurgery (SRS)

Answer

Conventional fractionated radiotherapy

Answer

Total body irradiation

Answer

Brachytherapy

Question 5

Which of the following is a common dose-limiting toxicity of cisplatin?

Accepted Answer

Nephrotoxicity

Answer

Pulmonary fibrosis

Answer

Cardiotoxicity

Answer

Hepatotoxicity

Question 6

Hormonal therapy with tamoxifen is most appropriate for which breast cancer receptor profile?

Accepted Answer

Estrogen receptor-positive

Answer

HER2-positive, ER-negative

Answer

Triple-negative

Answer

PR-negative, ER-negative