A 60-year-old diabetic patient develops hypoglycemia while on a sulfonylurea. Which mechanism directly causes insulin secretion with this drug class?
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A
Activation of GLP-1 receptors on beta cells
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B
Closure of ATP-sensitive potassium channels in beta cells
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C
Inhibition of alpha-glucosidase in the intestinal brush border
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D
Activation of PPAR-gamma receptors in adipose tissue