Free Master of Pharmacy: Pharmacokinetics and Pharmacodynamics Questions and Answers

Question 1

What percentage of the medication entering the systemic circulation is unchanged?

Accepted Answer

Bioavailability

Answer

Metabolism

Answer

Drug displacement

Answer

Elimination

Question 2

What best defines how the body reacts to the drug?

Accepted Answer

Pharmacokinetics

Answer

Pharmacodynamics

Answer

Physiology

Answer

Microbiology

Question 3

Which of the following is an issue with taking oral medications?

Accepted Answer

A and B

Answer

First pass effect

Answer

Low bioavailability

Answer

Overdose overcome by antidotes

Question 4

For a drug that strongly binds to peripheral tissues, what would be the volume of distribution (Vd)?

Accepted Answer

High

Answer

Unchanged

Answer

Cannot be determine

Answer

Low

Question 5

What happens when medicines enter the plasma?

Accepted Answer

Absorption

Answer

Elimination

Answer

Metabolism

Answer

Distribution

Question 6

What is one benefit of using sublingual administration?

Accepted Answer

All of the above

Answer

Avoid harsh GI environment

Answer

Avoid first pass-metabolism

Answer

Convenient

Question 7

What is a drawback of intramuscular (IM) administration?

Accepted Answer

B and C

Answer

Larger volumes can be used

Answer

Can affect lab tests

Answer

Painful

Question 8

In what location can one find extensive fenestrations or slit junctions?

Accepted Answer

Liver

Answer

Skin

Answer

Bone

Answer

Brain

Question 9

Among the provided options, which route exhibits the greatest bioavailability?

Accepted Answer

IV

Answer

SC

Answer

Oral

Answer

IM

Question 10

What would be the volume of distribution (Vd) for a drug that remains exclusively within the vascular compartment?

Accepted Answer

Low

Answer

High

Answer

Unchanged

Answer

Cannot be determined