FREE Master of Pharmacy: Pharmaceutical Formulations and Dosage Forms Questions and Answers

Question 1

As soon as the punch goes into the die, the first step in making a tablet is elastic deformation.

Accepted Answer

FALSE

Answer

TRUE

Answer

Maybe

Answer

None of the above

Question 2

Even though direct compression keeps a drug from being exposed to heat and moisture, it doesn't really cut down on the number of steps needed to make a tablet.

Accepted Answer

FALSE

Answer

TRUE

Answer

Maybe

Answer

None of the above

Question 3

When making low-dose tablets of highly potent drugs by direct compression, the biggest problem is getting the drug content to be uniform and homogeneous enough.

Accepted Answer

TRUE

Answer

FALSE

Answer

Maybe

Answer

None of the above

Question 4

In general, the amount of force used to make a tablet is directly related to how hard it is and how easily it breaks.

Accepted Answer

FALSE

Answer

TRUE

Answer

Maybe

Answer

None of the above

Question 5

True lubricants reduce the force needed to eject a tablet by lowering the force left in the die wall.

Accepted Answer

FALSE

Answer

TRUE

Answer

Maybe

Answer

None of the above

Question 6

Microcrystalline cellulose can't be used to make a tablet of a large dose of a drug that doesn't pack down well.

Accepted Answer

FALSE

Answer

TRUE

Answer

Maybe

Answer

None of the above

Question 7

Choose the term from the list that best describes how it works inside a compressed tablet after it has been exposed to moisture. Mechanism of Action of Disintegrants: Croscarmellose

Accepted Answer

Deformed fiber-shaped particles swell primarily radially and tend to straighten out

Answer

Recovers shape with little or no increase in volume

Answer

Overall swelling - a significant increase in volume

Answer

None of the above

Question 8

Choose the term from the list that best describes how it works inside a compressed tablet after it has been exposed to moisture. Mechanism of Action of Disintegrants: Starch

Accepted Answer

Recovers shape with little or no increase in volume

Answer

Overall swelling - a significant increase in volume

Answer

Deformed fiber-shaped particles swell primarily radially and tend to straighten out

Answer

None of the above

Question 9

Choose the term from the list that best describes how it works inside a compressed tablet after it has been exposed to moisture. Mechanism of Action of Disintegrants: Sodium starch glyconate

Accepted Answer

Overall swelling - a significant increase in volume

Answer

Recovers shape with little or no increase in volume

Answer

Deformed fiber-shaped particles swell primarily radially and tend to straighten out

Answer

None of the above

Question 10

This is about how the next tablet for a new medicine should be made. Wet granulation is used to make the tablets, and the drug is known to be hard to dissolve: xy1000(active) ....................................350mg
Lactose, USP Powder .......................106mg
Microcrystalline cellulose ...............90 mg
PVP ...........................................................30mg
Sodium starch glycolate NF ............18mg
Magnesium stearate ...........................6mg
Total Tablet Weight 600mg
If magnesium stearate was replaced in the formula with an equal amount of calcium stearate, the dissolution rate of xy1000 from the tablets would be expected to _____?

Accepted Answer

have a little effect on

Answer

cannot predict without more information

Answer

increase

Answer

decrease