Medical Laboratory Technician Exam Medical Laboratory Technician Hematology and Coagulation Questions and Answers 3

Question 1

Which red blood cell inclusion is identified using a supravital stain such as new methylene blue?

Accepted Answer

Heinz bodies

Answer

Heinz bodies are denatured hemoglobin inclusions that require supravital staining with new methylene blue or crystal violet for visualization.

Question 2

In von Willebrand disease type 1, which laboratory finding is most expected?

Accepted Answer

Prolonged bleeding time with decreased vWF antigen

Answer

Type 1 von Willebrand disease is a partial quantitative deficiency of vWF, leading to prolonged bleeding time and decreased vWF antigen levels.

Question 3

A peripheral blood smear reveals teardrop cells (dacrocytes), nucleated red blood cells, and immature granulocytes. This leukoerythroblastic picture is most suggestive of which condition?

Accepted Answer

Myelofibrosis

Answer

A leukoerythroblastic blood picture with dacrocytes is the classic peripheral smear finding in myelofibrosis due to marrow replacement by fibrosis.

Question 4

What is the principle behind the prothrombin time (PT) test?

Accepted Answer

Tissue factor activates the extrinsic pathway in recalcified plasma

Answer

The PT test measures the extrinsic and common pathways by adding tissue thromboplastin (tissue factor) and calcium to citrated plasma and timing clot formation.

Question 5

Which cell line is most characteristically elevated in chronic myelogenous leukemia (CML) during the chronic phase?

Accepted Answer

Granulocytic series with basophilia

Answer

CML in chronic phase shows marked granulocytic proliferation with a left shift and characteristic absolute basophilia in the peripheral blood.

Medical Laboratory Technician Exam Practice Test

Medical Laboratory Technician Exam Practice Test

Medical Laboratory Technician Exam Medical Laboratory Technician Hematology and Coagulation Questions and Answers 3